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MRI诊断孕中期胎儿胼胝体发育不良的临床价值研究 被引量:1

Clinical Value of MRI in the Diagnosis of Fetal Agenesis of Corpus Callosum in the Second Trimester
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摘要 目的 研究核磁共振(MRI)诊断孕中期胎儿胼胝体发育不良(ACC)的临床价值。方法 选取在我院孕检过程中怀疑胎儿胼胝体发育不良的孕中期孕妇60例,进行MRI检查,与超声检查、出生后或引产后结果对比,分析MRI诊断孕中期胎儿胼胝体发育不良的价值。结果 MRI检查诊断ACC符合率明显高于超声检查(P<0.05);误诊或漏诊率明显小于超声检查(P<0.05)。37例MRI诊断为完全性ACC,T2WI序列表现:横轴位见双侧侧脑室分离;第三脑室不同程度扩张并向头侧移位;侧脑室前角向外侧突,并呈“羊角”状;透明隔消失;侧脑室后角略增宽,部分呈“泪滴”状改变;正中矢状位未显示胼胝体,大脑内侧面的脑沟脑回呈放射状排列。20例诊断为部分性或可疑性ACC的MRI检查表现为胼胝体部分消失或者显示不清,双侧枕角扩大,纵裂池处局部增宽或合并囊肿,部分胎儿透明隔仍可见,第三脑室扩张可不明显,胼胝体周微动脉下陷。结论 产前MRI检查可帮助筛查胎儿胼胝体发育不良的问题,有助于明确诊断,可作为辅助检查手段在临床上推广使用。 Objective To study the clinical value of MRI in the diagnosis of fetal agenesis of corpus callosum(ACC)in the second trimester. Methods 60 pregnant women in the second trimester who were suspected of fetal ACC during the pregnancy examination in the hospital were selected for MRI examination. MRI results were compared with ultrasound examination and post-natal or post-induction results. The value of MRI in diagnosing fetal ACC in the second trimester was analyzed. Results The coincidence rate of ACC of MRI examination was significantly higher than that of ultrasound examination(P<0.05),and the misdiagnosis rate or missed diagnosis rate was significantly lower than that of ultrasound examination(P<0.05). 37 cases were diagnosed as complete ACC by MRI,and T2WI sequence manifestations showed that bilateral lateral ventricles were separated in the horizontal axis,the third ventricle was expanded to varying degrees and shifted to the cephalic side,and the anterior angle of the lateral ventricles was protruded laterally to the outside in sheep-horn shape,septum pellucidum was disappeared,the posterior angle of the lateral ventricles was slightly widened with partially teardrops-shaped change,the median sagittal section did not show the corpus callosum and the sulcus gyrus on the inner side of the brain was arranged radially. 20 cases were diagnosed as partial or suspicious ACC,and MRI showed that the corpus callosum partially disappeared or showed unclear,bilateral occipital angle was enlarged,longitudinal fissure cisterns were partially widened or associated with cysts,part of the fetal septum pellucidum was still visible,the dilation of third ventricle was not obvious,and the arterioles around the corpus callosum were depressed. Conclusion Prenatal MRI can help to screen the fetal agenesis of corpus callosum and help confirm the diagnosis,and can be used as an auxiliary examination method in clinical promotion and application.
作者 刘春玲 梁中华 刘义勇 王飞 朱承峰 葛岚 LIU Chun-ling;LIANG Zhong-hua;LIU Yi-yong;WANG Fei;ZHU Cheng-feng;GE Lan(Department of Radiology,Dalian women and Children Medical Center(Group),Dalian 116021,Liaoning Province,China)
出处 《中国CT和MRI杂志》 2023年第2期134-136,共3页 Chinese Journal of CT and MRI
关键词 MRI 胎儿胼胝体发育不良 诊断价值 孕中期 MRI Fetal Agenesis of Corpus Callosum Diagnostic Value Second Trimester
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