摘要
目的:分析特发性肺纤维化(IPF)中医康复应用并对其应用现状进行分析。方法:检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库和PubMed自建库至2020年12月收录的IPF中医康复研究,并对纳入的随机对照研究行偏倚风险评估。提取数据并对样本量、干预措施、腧穴应用,结局指标等进行频次统计和定性描述。结果:纳入24篇文献,偏倚风险相对较高,样本量相对较小。康复措施分别为中药离子导入7篇,针刺5篇,灸法、埋线、穴位贴敷各3篇,余较少;频次较高的腧穴有肺俞、膻中、大椎、定喘、肾俞、膏肓、脾俞、足三里;涉及的处方多为自拟方;康复的疗程及时间不尽相同。频次>3的结局指标有有效率、肺功能、中医证候/症状积分、影像学改变、6 min步行距离。结论:IPF中医康复研究较少,方法学质量较低,缺乏统一的标准、规范,需建立IPF的中医康复应用规范,提高研究设计水平,开展多中心、大样本的临床研究,为临床应用提供高质量的证据。
Objective: To analyze the application of traditional Chinese medicine in rehabilitation of idiopathic pulmonary fibrosis(IPF) and its current situation. Methods: The IPF TCM rehabilitation studies included in CNKI,Wanfang Database,Vip Database,China Biomedical Literature Database and PubMed self built database up to December 2020 were retrieved,and the risk of bias was assessed for the included randomized controlled studies. Data were extracted and frequency statistics and qualitative description were made on sample size,intervention measures,acupoint application,outcome indicators,etc. Results: The risk of bias was relatively high and the sample size was relatively small in 24 articles. The rehabilitation measures included 7 articles of iontophoresis of traditional Chinese medicine,5 articles of acupuncture,3 articles of moxibustion,catgut embedding,and acupoint application respectively,and the rest were less;The acupoints with higher frequency are Feishu(BL 13),Danzhong(RN 17),Dazhui(DU 14),Dingchuan(EX-B1),Shenshu(BL 23),Gaohuang(BL 43),Pishu(BL 20),Zusanli(ST 36);Most prescriptions involved are self-prepared;The course and time of rehabilitation vary. The outcome indicators of frequency>3 were efficiency,pulmonary function,TCM syndrome/symptom score,imaging changes,and 6 min walking distance. Conclusion: There is less research on traditional Chinese medicine rehabilitation of IPF,the quality of methodology is low,and there is a lack of unified standards and norms. It is necessary to establish the application norms of traditional Chinese medicine rehabilitation of IPF,improve the level of research design,carry out multi center,large sample clinical research,and provide high-quality evidence for clinical application.
作者
韩伟红
王明航
李建生
王佳佳
阮欢荣
谢洋
HAN Wei-hong;WANG Ming-hang;LI Jian-sheng;WANG Jia-jia;RUAN Huan-rong;XIE Yang(Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Henan Province&Education Ministry of P.R.China,Henan Key Laboratory of Chinese Medicine for Respiratory Disease,Henan University of Chinese Medicine,Zhengzhou 450046,China;Respiratory Department,The First Affiliated Hospital of Henan University of CM,Zhengzhou 450000,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2023年第2期875-880,共6页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金面上项目(No.81973779)
河南省自然科学基金项目(No.212300410056)
河南省中医药科学研究专项课题(No.2018JDZX114,No.20-21ZY2186)
河南省特色骨干学科中医学学科建设项目(No.STG-ZYXKY-2020001)。
关键词
特发性肺纤维化
中医康复
临床应用
文献
标准化
Idiopathic pulmonary fibrosis(IPF)
TCM rehabilitation
Clinical application
Literature
Standardization
