摘要
目的 探讨增强型体外反搏(EECP)联合药物治疗对抑郁发作患者社会功能及疗效的影响,为抑郁发作的治疗提供参考。方法 采用简单随机抽样法选取2019年5月-2020年3月在中南大学湘雅二医院精神科住院、符合《精神障碍诊断与统计手册(第5版)》(DSM-5)抑郁障碍或双相情感障碍抑郁发作诊断标准的患者66例为研究对象,按照随机数字表法分为研究组(n=36)和对照组(n=30),两组均接受常规药物治疗,研究组在此基础上接受EECP干预。于治疗前后采用汉密尔顿抑郁量表24项版(HAMD-24)和席汉失能量表(SDS)分别评定患者的抑郁症状和社会功能,并比较两组的疗效。结果 治疗后,研究组及对照组HAMD-24和SDS评分均低于治疗前,差异均有统计学意义(t=8.149、5.791、8.016、3.488,P均<0.01),研究组SDS评分低于对照组,差异有统计学意义(t=-3.008,P<0.01)。研究组治疗总有效率高于对照组,差异有统计学意义(90.63%vs. 63.33%,χ^(2)=8.725,P<0.05)。结论 EECP联合药物治疗可能有助于提升抑郁发作患者的社会功能并改善抑郁症状。
Objective To observe the effect of the enhanced external counterpulsation(EECP) combined with drug on social function and efficacy in patients with depressive episodes, so as to provide references for the treatment of depressive episodes.Methods A total of 66 hospitalized patients who was in hospital at department of psychiatry of the Second Xiangya Hospital of Central South University, met the criteria of Diagnostic and Statistical Manual of Mental Disorders,fifth edition(DSM-5) diagnosis of depressive episode or bipolar disorder depressive episode from May 2019 to March 2020 were included by simple random sampling.The participants were divided into study group(n=36) and control group(n=30) according to the random number table method. Both groups received conventional drug treatment, and the study group recieved the EECP intervention at same time. The Depression symptoms and social function were assessed before and after treatment by using Hamilton Depression Scale-24 item(HAMD-24) and Sheehan Disability Scale(SDS). Treatment efficacy of the two groups was compared.Results After the intervention, the HAMD-24and SDS scores in both groups were lower than those before treatment, the differences were statistically significant(t=8. 149, 5. 791, 8. 016, 3. 488, P<0. 01). And the SDS score of the study group was siginficantly lower than that of the control group(t=-3. 008, P<0. 05). The total effective rate of treatment in the study group was higher than that of the control group, and the difference was statistically significant(90. 63% vs. 63. 33%, χ^(2) =8. 725, P<0. 05).Conclusion EECP therapy combined with drug has better efficacy on the patients with depressive episodes, and it can improve social function effectively.
作者
渠婷婷
吴蓝珊
王润
刘聪聪
袁钦湄
杨峘
李则宣
曹玉萍
Qu Tingting;Wu Lanshan;Wang Run;Liu Congcong;Yuan Qinmei;Yang Huan;Li Zexuan;Cao Yuping(Department of Psychiatry of the Second Xiangya Hospital of Central South University,China National Clinical Research Center on Mental Disorders,Changsha 410011,China;The Fifth People's Hospital of Xiangtan,Xiangtan 411100,China;The First People's Hospital of Chenzhou,Chenzhou 423000,China)
出处
《四川精神卫生》
2023年第1期6-11,共6页
Sichuan Mental Health
基金
湖南省科技创新计划项目(项目名称:抑郁症院外智能综合干预系统的研究与示范,项目编号:2021SK2029)。
关键词
抑郁发作
双相障碍抑郁发作
体外反搏
抑郁症状
社会功能
疗效
Depressive episode
Bipolar disorder depressive episode
Enhanced external counterpulsation
Depressive symptoms
Social function
Efficacy
