摘要
肝内胆管细胞癌(ICC)是一种高度侵袭性的原发性肝脏恶性肿瘤,其发病隐匿、早期症状不典型、预后差。外科根治性手术切除是治疗ICC的唯一有效手段。淋巴结转移(LNM)作为影响ICC患者手术预后最重要的危险因素之一,已有多数指南建议在ICC根治性切除术中常规行淋巴结清扫(LND)。然而,关于ICC根治性切除术中LND的范围及其对患者预后的价值,目前仍存在较大争议。故笔者结合国内外现有的研究,对ICC根治性切除术中LND所存在的争议及问题的研究进展进行综述,以期为ICC的临床治疗提供参考。
Intrahepatic cholangiocarcinoma(ICC)is a highly aggressive primary liver malignant tumor with insidious onset,atypical early symptoms,and poor prognosis.Radical surgical resection is the only effective treatment for ICC.Lymph node metastasis(LNM)is one of the most important risk factors affecting the prognosis of patients with ICC.Most guidelines suggest routine lymph node dissection(LND)during radical resection of ICC.However,the extent of LND in radical ICC resection and its prognostic value is still controversial.Therefore,the authors review the research progress on the controversies and problems of LND in radical ICC resection combined with the existing research results at home and abroad to provide a reference for the clinical treatment of ICC.
作者
赵泽坤
魏丰贤
王建雄
周志明
马尚贤
徐小东
ZHAO Zekun;WEI Fengxian;WANG Jianxiong;ZHOU Zhiming;MA Shangxian;XU Xiaodong(Department of General Surgery,the Second Hospital of Lanzhou University,Lanzhou 730000,China)
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2023年第2期261-268,共8页
China Journal of General Surgery
基金
甘肃省自然科学基金资助项目(21JR11RA103)
甘肃省青年科技基金资助项目(21JR1RA161)
兰州大学第二医院萃英科技创新计划资助项目(CY2019-BJ02)。
关键词
胆管肿瘤
胆管
肝内
淋巴结切除术
综述
Bile Duct Neoplasms
Bile Ducts,Intrahepatic
Lymph Node Excision
Review
