摘要
目的:观察红藤汤外敷联合中药保留灌肠治疗慢性盆腔炎的临床疗效。方法:将60例慢性盆腔炎患者按照随机数字表法分为对照组和观察组,每组各30例。两组均给予常规西药治疗,对照组予以红藤汤保留灌肠,观察组在对照组的基础上联合红藤汤外敷。比较两组患者的临床疗效及治疗前后中医证候积分、妇科检查情况、炎症因子[肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、C反应蛋白(C reactive protein,CRP)、单核细胞趋化蛋白-1(monocyte chemotactic protein-1,MCP-1)、粒细胞-巨噬细胞集落刺激因子(granulocyte-macrophage colony stimulating factor,GM-CSF)]、子宫血流动力学指标[子宫搏动指数(pulsation index,PI)、阻力指数(resistance index,RI)、最大峰值流速(maximum peak flow rate,PFE)]、血液流变学指标[血浆黏度(plasma viscosity,PV)、红细胞沉降率(erythrocyte sedimentation rate,ESR)、红细胞比容(hematocrit,Hct)]变化情况。结果:两组患者治疗后中医证候积分低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。对照组有效率为70.00%,观察组有效率为93.33%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后宫颈触痛、子宫活动受限、宫体/附件压痛评分、炎性包块直径、盆腔积液最深径低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后TNF-α、CRP、GM-CSF及MCP-1低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后PV、ESR及Hct低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。结论:红藤汤外敷联合中药保留灌肠治疗慢性盆腔炎,可改善患者的临床症状,抑制炎性反应,促进血液循环。
Objective:To observe the clinical efficacy of Caulis Sargentodoxae Decoction for external application combined with retention enema of Chinese medicinals on chronic pelvic inflammatory disease.Methods:A total of 60 patients with chronic pelvic inflammatory disease were divided into the control group and the observation group according to random number table,with 30 cases in each group.Both groups were treated with conventional Western medicine,then the control group was additionally treated with Caulis Sargentodoxae Decoction for retention enema,while the observation group was additionally treated with external application with Caulis Sargentodoxae Decoction on the basis of the control group.The clinical efficacy,the changes of the score of TCM syndromes,gynecological examination,inflammatory factors [including tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),monocyte chemoattractant protein-1(MCP-1),granulocyte-macrophage colony stimulating factor(GM-CSF)],tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),monocyte chemoattractant protein-1(MCP-1),granulocyte-macrophage colony stimulating factor(GM-CSF)],hemorheology indexes [including plasma viscosity(PV),erythrocyte sedimentation rate(ESR) and hematocrit(Hct)] of the two groups before and after treatment were compared.Results:The TCM syndrome score of the two groups after treatment was lower than that of the same group before treatment,and the observation group′s was lower than that of the control group,and the difference was statistically significant(P<0.05).The effective rate was 70.00% in the control group and 93.33% in the observation group.The difference between the two groups was statistically significant(P<0.05).After treatment,the cervical tenderness,uterine activity limitation,uterine body/accessory tenderness score,inflammatory mass diameter and the deepest diameter of pelvic effusion in the two groups were lower than those of the same group before treatment,and the observation group′s above indexes were lower than those of the control group,and all the differences were statistically significant(P<0.05);TNF-α,CRP,GM-CSF and MCP-1 in the two groups were lower than those of the same group before treatment,and the observation group′s above indexes were lower than those of the control group,and all the differences were statistically significant(P<0.05);PV,ESR and Hct in the two groups were lower than those of the same group before treatment,and the observation group′s above indexes were lower than those of the control group,and all the differences were statistically significant(P<0.05).Conclusion:Caulis Sargentodoxae Decoction for external application combined with retention enema of Chinese medicinals can improve the clinical symptoms of patients with chronic pelvic inflammatory disease,inhibit inflammatory reaction and promote blood circulation.
作者
欧阳晓玲
卢淑芳
魏桂凤
OUYANG Xiao-ling;LU Shu-fang;WEI Gui-feng(Anyuan County People′s Hospital,Anyuan,Jiangxi,China,342100)
出处
《河南中医》
2023年第3期436-440,共5页
Henan Traditional Chinese Medicine
基金
江西省赣州市科技计划项目(GZ2021ZSF561)。
关键词
慢性盆腔炎
红藤汤
中药外敷
保留灌肠
盐酸左氧氟沙星片
甲硝唑片
中西医结合疗法
chronic pelvic inflammatory disease
Caulis Sargentodoxae Decoction
retention enema
external application of Chinese medicinals
Levofloxacin Hydrochloride Tablets
Metronidazole Tablets
integrated traditional Chinese and Western medicine
