摘要
冠心病是以动脉粥样硬化为病理基础的疾病,归属于中医学“胸痹”“真心痛”等范畴。基于现代医学关于冠心病的病理生理机制,结合中医学病因病机认识,发现“瘀”“毒”相互兼夹、互结从化是冠心病发生发展的关键病机。笔者通过探讨瘀毒理论源流,分析动脉硬化类疾病瘀毒互结病机的致病特点,梳理活血解毒法干预相关疾病的临床应用和基础研究进展,为以冠心病为代表的动脉粥样硬化类疾病的病证结合防治提供思路。
Coronary heart disease(CHD)is based on atherosclerosis(AS),which belongs to the categories of‘chest pain’or‘chest obstruction’in Traditional Chinese Medicine(TCM).Based on the pathophysiological mechanism of CHD in modern medicine,combined with the understanding of the etiology and pathogenesis of TCM,it is found that the key pathogenesis of CHD is‘blood stasis’and‘toxin’mutual integration.By discussing the connotation and origin of the theory of blood stasis and toxin,the article summarized the pathogenic characteristics of the pathogenesis of the interaction of blood stasis and toxin in atherosclerotic diseases and organized the progress in clinical application and basic research of the method of activating blood circulation and detoxifying,which provides ideas of combining disease and syndrome for the prevention and treatment of atherosclerotic diseases represented by CHD with integrated TCM and western medicine.
作者
高铸烨
宋烨闻
姜众会
林宫羽
李智
曲华
杜天依
GAO Zhu-ye;SONG Ye-wen;JIANG Zhong-hui;LIN Gong-yu;LI Zhi;QU Hua;DU Tian-yi(National Clinical Research Center for Chinese Medicine Cardiology,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;Graduate School of Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2023年第3期953-956,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家“十二五”科技支撑计划(No.2013BAI02B01)
国家自然科学基金项目(No.82274508)。
关键词
冠心病
瘀
毒
瘀毒
病机
Coronary heart disease
Blood stasis
Toxin
Stasis-toxin
Pathogenesis
