摘要
目的:分析大柴胡汤合桂枝茯苓丸汤剂治疗气滞痰阻血瘀型混合型高脂血症患者的临床效果。方法:选取2020年6月-2021年12月佛山市中医院禅城高新区医院收治的气滞痰阻血瘀型混合型高脂血症患者90例为观察对象,根据随机数字表法分为对照组与观察组,各45例。观察组给予大柴胡汤合桂枝茯苓丸汤剂治疗,对照组给予辛伐他汀片治疗,比较两组患者血脂水平、安全性指标、治疗效果。结果:治疗后,两组患者非高密度脂蛋白胆固醇(N-HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、总胆固醇(TC)水平均降低,高密度脂蛋白胆固醇(HDL-C)水平均升高,观察组N-HDL-C、LDL-C、TG、TC水平低于对照组,HDL-C水平高于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论:大柴胡汤合桂枝茯苓丸汤剂治疗气滞痰阻血瘀型混合型高脂血症的效果显著,可有效改善患者血脂水平,安全性较高。
Objective:To analyze the clinical effect of Dachaihu decoction combined with Guizhi Fuling pill decoction in treating patients with mixed hyperlipidemia with Qi stagnation,phlegm obstruction and blood stasis.Methods:Ninety patients with mixed hyperlipidemia with Qi stagnation,phlegm blockage and blood stasis admitted to Chancheng High-tech Zone Hospital of Foshan Hospital of Traditional Chinese Medicine from June 2020 to December 2021 were selected as observation subjects and divided into control group and observation group according to random number table method,with forty-five cases in each group.The observation group was treated with Dachaihu decoction combined with Guizhi Fuling pill decoction,while the control group was treated with simvastatin tablets.The blood lipid levels,safety indexes,and treatment effects of the two groups were compared.Results:After treatment,the levels of non-high-density lipoprotein cholesterol(N-HDL-C),low-density lipoprotein cholesterol(LDL-C),triglyceride(TG)and total cholesterol(TC)decreased and the levels of high-density lipoprotein cholesterol(HDL-C)increased in both groups.The levels of N-HDL-C,LDL-C,TG,and TC in the observation group were lower than those in the control group,and the levels of HDL-C in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Dachaihu decoction combined with Guizhi Fuling pill decoction can effectively improve blood lipid levels in patients with mixed hyperlipidemia with Qi stagnation,phlegm blockage and blood stasis,and has a high safety profile.
作者
卢健胜
胡宗仁
梁斯娜
Lu Jian-sheng;Hu Zong-ren;Liang Si-na(Chancheng High-tech Zone Hospital of Foshan Hospital of Traditional Chinese Medicine,Foshan 528000,Guangdong Province,China)
出处
《中外医药研究》
2022年第15期88-90,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
大柴胡汤
气滞痰阻血瘀型
桂枝茯苓丸
血脂
混合型高脂血症
Dachaihu decoction
Qi stagnation,phlegm blockage,blood stasis type
Guizhi Fuling pill
Blood lipid
Mixed hyperlipidemia
