摘要
目的:探究桉柠蒎肠溶软胶囊联合吸入用乙酰半胱氨溶液治疗慢性阻塞性肺疾病(COPD)的临床效果。方法:选择厦门市同安区中医医院2020年6月至2022年2月收治的60例COPD患者,按用药不同分为两组,每组30例,其中对照组患者给予吸入用乙酰半胱氨溶液进行治疗,观察组则实施桉柠蒎肠溶软胶囊联合吸入用乙酰半胱氨溶液进行治疗,比较两组患者治疗效果。结果:与对照组比较,观察组患者总有效率更高,治疗后第1秒用力呼气量(FEV1)、第1秒用力呼气量占用力肺活量比值(FEV1/FVC)均高于对照组,临床症状消失时间短于对照组,慢性阻塞性肺疾病评估测试量表(CAT)评分低于对照组,差异具有统计学意义(P<0.05);两组患者不良反应比较差异无统计学意义(P>0.05)。结论:桉柠蒎肠溶软胶囊联合吸入用乙酰半胱氨溶液治疗COPD患者,在获得较好的临床效果的同时不增加不良反应,安全性较高,能有效改善患者肺功能、呼吸情况。
Objective To explore the clinical effect of eucalyptus pine-enteric soft capsules combined with inhaled acetyl cysteamine solution in the treatment of chronic obstructive pulmonary disease(COPD).Methods A total of 60 COPD patients admitted to Xiamen Tong'an District Hospital of Traditional Chinese Medicine from June 2020 to February 2022 were divided into two groups with 30 patients in each group.The control group was treated with acetyl cysteamine solution for inhalation,while the observation group was treated with eucalyptus and lime pine-enteric soft capsules combined with acetyl cysteamine solution for inhalation.The therapeutic effect of the two groups was compared.Results Compared with the control group,the total effective rate in the observation group was higher,the forced expiratory volume in the first second(FEV1),the ratio of forced expiratory volume in the first second to forced vital capacity(FEV1/FVC)after treatment were higher than those in the control group,the time of symptom disappearance was shorter than that in the control group,and the score of chronic obstructive pulmonary Disease Evaluation Test Scale(CAT)was lower than the control group.The difference was statistically significant(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion In the treatment of COPD patients with eucalyptus lime pine-enteric soft capsules combined with inhaled acetyl cysteamine solution,good clinical effects were achieved without increasing adverse reactions,with high safety,and effective improvement of lung function and respiratory conditions.
作者
郑翠洋
林山寨
ZHENG Cui-yang;LIN Shan-zhai(Xiamen Tong'an District Hospital of Traditional Chinese Medicine,Fujian Xiamen 361000)
出处
《深圳中西医结合杂志》
2023年第3期113-115,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
慢性阻塞性肺疾病
桉柠蒎肠溶软胶囊
吸入用乙酰半胱氨溶液
Chronic obstructive pulmonary disease
Eucalyptus lime pine-intestinal soft capsules
Acetyl cysteamine solution for inhalation
