摘要
新辅助治疗可缩小恶性肿瘤、破坏恶性肿瘤细胞以及降低手术难度。术前接受新辅助治疗已逐渐成为肿瘤患者常见治疗方式之一,其对机体免疫系统、心血管系统、呼吸系统及全身多器官产生重要影响,可能关系到围手术期管理决策。文章就接受新辅助治疗的恶性肿瘤患者的手术时机、术前预康复策略、麻醉管理方式及要点等进行综述,以期为此类患者临床麻醉管理提供一定参考。此外,如何改善接受新辅助治疗患者的预后,确定最佳麻醉方式及药物使用,有待进一步研究。
Neoadjuvant therapy can shorten malignant tumor,destroy malignant tumor cells and reduce surgical difficulties.Preoperative neoadjuvant therapy has become one of the common treatment modalities for patients with malignant tumor,with pivotal effects on the immune system,cardiovascular system,respiratory system,and functions of multiple organs,and is relevant to perioperative management strategies.This review will summarize the perioperative management of patients with neoadjuvant therapy,including timing of surgery,prehabilitation strategies,and anesthesia management strategies,so as to provide reference for improvement in clinical anesthesia management.In addition,further research is needed to improve the prognosis of patients receiving neoadjuvant therapy and to determine the optimal anesthesia practice and medication.
作者
王汇贤
翟蓉
王薇
薄禄龙
Wang Huixian;Zhai Rong;Wang Wei;Bo Lulong(Faculty of Anesthesiology,Changhai Hospital,Naval Medical University,Shanghai 200433,China)
出处
《国际麻醉学与复苏杂志》
CAS
2023年第2期193-197,共5页
International Journal of Anesthesiology and Resuscitation
基金
海军军医大学第一附属医院"234学科攀峰计划"(2020YXK053)。
关键词
肿瘤
新辅助治疗
麻醉
器官功能
围手术期
Tumor
Neoadjuvant therapy
Anesthesia
Organ function
Perioperative period
