摘要
围产期奶牛极易发生由于能量摄入不足但输出加剧导致的能量负平衡(NEB),而NEB的发生与奶牛在围产期形成的过氧化应激状态密切相关。过氧化应激造成的氧化损伤对奶牛的生产性能和健康危害巨大,通过营养调控手段缓解过氧化应激造成的氧化损伤是亟需解决的重要课题之一。抗氧化剂(AOX)主要包括酶类抗氧化剂和非酶类抗氧化剂,但酶类抗氧化剂的实践应用具有种种局限性,因此通过给围产期奶牛补充非酶类抗氧化剂,使其作用于各种酶类抗氧化剂间接缓解过氧化应激状态是一种有效的实施途径。本文从围产期奶牛的过氧化应激状态,AOX的生理功能与作用机制及过量添加非酶类抗氧化剂降低抗氧化系统能力等方面进行综述,为相关研究提供参考价值。
Transition dairy cows are prone to have negative energy balance(NEB)caused by insufficient energy intake and increased output,which further induces a peroxide stress state.Oxidative damage caused by peroxide stress will cause significant harm to the production performance and health of dairy cows.Alleviating the oxidative in transition dairy cows through nutritional regulation strategy becomes an urgent issue.Antioxidants(AOX)mainly include enzymatic antioxidants and non-enzymatic antioxidants.Due to the limitations of enzymatic oxidants,using non-enzymatic antioxidants to regulate the activity of enzymatic antioxidants and then indirectly alleviate the peroxidative stress state has been an effective strategy in transition dairy cows.To provide better guidance on health regulation in dairy cows,we summarized the mechanism and research progress of the AOX in alleviating the peroxidative stress state of dairy cows during the transition period.
作者
马俊林
姚军虎
战余铭
张俊
MA Junlin;YAO Junhu;ZHAN Yuming;ZHANG Jun(College of Animal Science and Technology,Northwest A&F University,Shaanxi Yangling 712000,China;Shandong Feed and Veterinary Drug Quality Inspection Center,Shandong Jinan 250109,China)
出处
《中国畜牧杂志》
CAS
CSCD
北大核心
2023年第4期31-38,共8页
Chinese Journal of Animal Science
基金
国家自然科学基金(32102570)
中国博士后科学基金(2021M702691)
中央高校基本科研业务费专项资金资助(2452020188)。
关键词
抗氧化剂
氧化应激
围产期
奶牛
Antioxidants
Oxidative stress
Transition period
Dairy cows
