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输尿管软镜碎石术与经皮肾镜碎石术治疗肾结石的效果及对术后恢复和肾功能的影响比较 被引量:9

Comparison of the Efficacy of Flexible Ureteroscopic Lithotripsy and Percutaneous Nephrolithotomy in the Treatment of Renal Calculi and Their Effects on Postoperative Recovery and Renal Function
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摘要 目的:比较输尿管软镜碎石术(FURL)与经皮肾镜碎石术(PCNL)治疗肾结石的效果及对术后恢复和肾功能的影响。方法:以2018年3月-2021年4月湖南省直中医医院收治的80例肾结石患者为研究对象,随机分为FURL组(n=40)和PCNL组(n=40)。FURL组行FURL治疗,PCNL组行PCNL治疗。比较两组手术一般情况、术后恢复情况及肾功能[血清肌酐(Scr)、尿素氮(BUN)、血尿酸(BUA)]。结果:与PCNL组相比,FURL组术中出血量更少、Hb下降值更小、下床时间和术后住院时间均更短、术后1 d和2 d时疼痛视觉模拟评分法(VAS)评分均更低(P<0.05)。两组手术时间、一期结石清除率(85.00%vs. 87.50%)、术后并发症总发生率(15.00%vs. 17.50%)比较,差异均无统计学意义(P>0.05)。FURL组术后Scr、BUN、BUA水平均明显低于PCNL组(P<0.05)。结论:FURL与PCNL治疗肾结石的效果相当,其中FURL对患者机体的创伤更小,表现为患者术中出血量少、术后疼痛轻,对肾功能的损伤更小,术后住院时间更短,恢复更快。 Objective:To compare the efficacy of flexible ureteroscopic lithotripsy(FURL)and percutaneous nephrolithotomy(PCNL)in the treatment of renal calculi and their effects on postoperative recovery and renal function.Method:A total of 80 patients with renal calculi admitted to Hunan Provincial Directly Affiliated TCM Hospital from March 2018 to April 2021 were randomly divided into FURL group(n=40)and PCNL group(n=40).The FURL group was treated with FURL,and the PCNL group was treated with PCNL.The general situation of operation,postoperative recovery and renal function[serum creatinine(Scr),blood urea nitrogen(BUN),blood uric acid(BUA)]were compared between the two groups.Result:Compared with PCNL group,intraoperative blood loss and Hb decline were less,ambulation time and postoperative hospital stay were shorter and visual analogue scale(VAS)scores at 1 d,2 d after operation were lower in FURL group(P<0.05).There were no significant differences in operation time,primary stone clearance rate(85.00%vs.87.50%)and total incidence of postoperative complications(15.00%vs.17.50%)between the two groups(P>0.05).The levels of Scr,BUN and BUA in FURL group were significantly lower than those in the PCNL group(P<0.05).Conclusion:FURL is equivalent to PCNL in the treatment of renal calculi,but FURL has less trauma to the patient's body,which is characterized by less intraoperative blood loss,less postoperative pain,less damage to renal function,shorter postoperative hospital stay and faster recovery.
作者 安玉婵 邓旭 AN Yuchan;DENG Xu(Hunan University of Chinese Medicine,Changsha 410208,China)
出处 《中国医学创新》 CAS 2023年第9期10-14,共5页 Medical Innovation of China
关键词 输尿管软镜碎石术 经皮肾镜碎石术 肾结石 术后恢复 肾功能 Flexible ureteroscopic lithotripsy Percutaneous nephrolithotomy Renal calculi Postoperative recovery Renal function
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