摘要
目的探讨输尿管支架管辅助治疗肾结核患者的临床疗效。方法文章选择青海省第四人民医院2020年1月-2021年12月收治的93例患者随机分为观察组(n=47)和对照组(n=46)。所有患者均给予HRZE抗结核药物治疗,观察组在此基础上联合输尿管支架管辅助治疗。观察比较两组临床治愈率及肾切除率,治疗前后肾盂分离度、肾实质厚度及新发发热、肉眼血尿、膀胱结核等并发症发生情况。结果观察组临床治愈39例,治愈率82.98%,显著高于对照组的45.65%;观察组肾切除8例(17.02%),低于对照组的25例(54.35%)。两组临床治愈率及肾切除率比较,差异有统计学意义(χ^(2)=14.148,P=0.000)。治疗后,观察组肾盂分离度减轻至(13.62±1.29)mm,对照组肾盂分离度增加至(32.15±2.64)mm(P<0.05),两组肾盂分离度比较,存在统计学差异(t=-42.860,P=0.000)。肾实质厚度比较,观察组肾实质厚度(19.33±1.79)mm较治疗前无明显变化(P>0.05),对照组肾实质厚度下降为(11.58±1.45)mm(P<0.05),两组肾实质厚度比较,存在统计学差异(t=22.966,P=0.000)。观察组新发发热、肉眼血尿、膀胱结核等并发症发生率为63.83%,高于对照组的32.61%,两组比较,差异有统计学意义(χ^(2)=9.074,P=0.003)。结论输尿管支架管辅助治疗肾结核临床治愈率高,可有效减轻肾盂分离,改善肾积水症状,维持肾实质厚度,减少肾实质损害,降低肾切除率,保护肾功能,值得推广应用。
Objective This study aims to investigate the clinical efficacy of ureteral stent in the adjuvant treatment of renal tuberculosis.Methods 93 patients in our hospital from January 2020 to December 2021 were randomly divided into observation group(n=47)and control group(n=46).All patients were treated with HRZE antituberculosis drugs,and the observation group was treated with ureteral stent on this basis.It observed and compared the clinical cure rate,nephrectomy rate,renal pelvis separation,renal parenchyma thickness,new fever,gross hematuria,bladder tuberculosis and other complication between the two groups before and after treatment Results 39 cases were cured in the observation group with the cure rate of82.98%,which significantly higherthan 45.65%in the control group.Renal resection was performed in 8 patients(17.02%)in the observation group,which lowerthan that of 25 patients(54.35%)in the control group.The clinical cure rate and nephrectomy rate of the two groups were statistically significant(χ^(2)=14.148,P=0.000).After treatment,the separation of renal pelvis in the observation group was reduced to(13.62±129)mm,while that of was increased to(32.15±2.64)mm in the control group(P<0.05).There was a statistical difference in the renal pelvis separation between the two groups(t=42.860,P=0.000).Compared with the thickness of renal parenchyma,it was(1933±1.79)mm in the observation group,which had no significant change compared with that before treatment(P>0.05).The thickness of renal parenchyma in the control group decreased to(1158±1.45)mm(P<0.05).The renal parenchyma thickness ofthe two groups was statistically different(t=22.966,P=0.000).The incidence of new fever,gross hematuria,bladder tuberculosis and other complication in the observation group was63.83%,higherthan that in the control group(32.61%).The difference between the two groups was statistically significant(χ^(2)=9.074,P=0.003).Conelusion The clinical cure rate of ureteral stent assisted treatment of renal tuberculosis is high.It effectively reduces the separation of renal pelvis,improves hydronephrosis,maintains the thickness of renal parenchyma,reduces the damage of renal parenchyma,reduces the rate of nephrectomy,and protects renal function.It is worth popularizing.
作者
王生鹏
李永芬
翟高杰
李正平
Wang Shengpeng;Li Yongfen;Zhai Gaojie;Li Zhengping(The Fourth People's Hospital of Qinghai Province,Xining,Qinghai 810000,China)
出处
《首都食品与医药》
2023年第9期24-26,共3页
Capital Food Medicine
关键词
输尿管支架管
肾结核
肾盂分离
肾实质厚度
肾积水
Ureteral stent
Renal tuberculosis
Separation of renal pelvis
Renal parenchyma thickness
Hydronephrosis
