摘要
目的:分析2016年重庆市肺癌发病率、死亡率与随访五年的生存率,为开展肺癌防治提供依据。方法:对2016年新报告的肺癌患者进行主动和被动随访,随访信息网络直报到重庆市肿瘤随访登记信息系统,采用SPSS 25.0统计分析发病率、标化发病率、死亡率、标化死亡率、生存率等指标。标化发病率与死亡率采用2000年第五次人口普查标准人口构成进行标化。不同性别与地区率的比较采用χ^(2)检验。采用生存分析寿命表法计算观察生存率,采用乘积极限法(Kaplan-Meier)计算平均生存时间,生存率的比较采用Log Rank of Mantel-Cox进行统计检验。结果:2016年重庆市肺癌发病率与标化发病率分别为79.13/10万与44.82/10万,男性发病率(110.33/10万)高于女性(46.77/10万)(χ^(2)=63.018,P<0.001),城市(87.65/10万)高于农村(75.86/10万)(χ^(2)=10.47,P=0.001)。肺癌死亡率与标化死亡率分别为65.96/10万与33.77/10万,男性死亡率(95.40/10万)高于女性(35.95/10万)(χ^(2)=64.43,P<0.001),城市(73.30/10万)高于农村(60.83/10万)(χ^(2)=12.28,P<0.001)。对18842例肺癌患者进行五年的随访,随访五年平均生存时间为2.11(2.07,2.14)年。1年、2年、3年、4年、5年生存率分别为41.84%、33.41%、29.97%、28.04%、26.54%,女性肺癌生存率均高于男性,差异有统计学意义(χ^(2)=80.05,P<0.001)。城市肺癌生存率均高于农村,差异有统计学意义(χ^(2)=271.78,P<0.001)。结论:重庆市肺癌发病率和死亡率高,生存率较低,重点应针对男性和农村地区开展肺癌的预防、早期筛查和规范的诊断治疗。
Objective:To analyze the incidence,mortality and survival rate of lung cancer in Chongqing,2016 and provide the suggestion for lung cancer prevention and control.Methods:Lung cancer cases reported from districts and counties in Chongqing entered into this study in 2016.All lung cancer cases were followed up for five years by active and passive follow up to survey the living status.All follow-up information was reported to Chongqing cancer registry and follow-up information system.Indicators such as the incidence,age standardization incidence rate by Chinese standardization population(ASIRC),mortality,age standardization mortality rate by Chinese standardization population(ASMRC),survival rate were calculated by SPSS 25.0.ASIRC and ASMRC was standardized by national standard population proportion in 2000.The difference of the incidence and mortality between male and female,urban and rural area was compared by Chi-square test.The observed survival rate was calculated by survival life table.The average survival life time was calculated by Kaplan-Meier.The difference of survival rate of lung cancer between male and female,urban and rural area was compared by Log Rank of Mantel-Cox.Results:The incidence and ASIRC of lung cancer were 79.13/100000 and 44.82/100000 respectively in Chongqing,2016.The incidence of lung cancer among male residents(110.33/100000)was higher than that among female residents(46.77/100000)(χ^(2)=63.018,P<0.001).The incidence of lung cancer in urban area(87.65/100000)was higher than that in rural area(75.86/100000)(χ^(2)=10.47,P=0.001).The mortality and ASMRC of lung cancer were 65.96/100000 and 33.77/100000 respectively in Chongqing,2016.The mortality of lung cancer among male residents(95.40/100000)was higher than that among female residents(35.95/100000)(χ^(2)=64.43,P<0.001).The mortality of lung cancer in urban area(73.30/100000)was higher than that in rural area(60.83/100000)(χ^(2)=12.28,P<0.001).A total of 18842 cases of lung cancer were followed up for five years.The average survival year of lung cancer was 2.11(2.07,2.14)years after five years of follow up.The survival rate of 1 year,2 years,3 years,4 years and 5 years were 41.84%,33.41%,29.97%,28.04%and 26.54%respectively.The survival rate of lung cancer among female residents was higher than that among male residents(P<0.05).The survival rate of lung cancer in urban area was higher than that in rural area(P<0.05).Conclusion:The incidence and mortality of lung cancer was high in Chongqing.However,the survival rate of lung cancer was low.It should be conducted the prevention,early screening,standard diagnosis and treatment targeting male and rural residents in Chongqing.
作者
丁贤彬
吕晓燕
焦艳
高旸
熊娟
陈婷
许杰
丁睿
DING Xianbin;LYU Xiaoyan;JIAO Yan;GAO Yang;XIONG Juan;CHEN Ting;XU Jie;DING Rui(Institute of Non-communicable Disease Control and Prevention,Chongqing Center for Disease Control and Prevention,Chongqing 400042,China;The Second People's Hospital of Yubei District,Chongqing 401147,China;First Clinical College of Chongqing Medical University,Chongqing 400016,China)
出处
《现代肿瘤医学》
CAS
北大核心
2023年第11期2116-2120,共5页
Journal of Modern Oncology
基金
重庆市科卫联合项目(编号:2021MSXM198)。
关键词
肺癌
发病率
死亡率
生存率
lung cancer
incidence
mortality
survival rate
