摘要
目的探讨分析左氧氟沙星联合胰岛素泵治疗2型糖尿病合并肺部感染对患者血糖水平、急性生理与慢性健康(Acute Physiological and Chronic HealthⅡ,APACHEⅡ)评分的影响。方法选取2020年9月—2021年9月麻城市人民医院重症医学科收治的80例糖尿病合并肺部感染患者为研究对象,采用随机数表法分为比较组(40例)和研究组(40例)。比较组采取左氧氟沙星以及常规控制血糖治疗,研究组在比较组基础上联用胰岛素泵治疗。分别比较两组的治疗效果。结果治疗前,两组糖化血红蛋白(HbA1c)、餐后2 h血糖(2 hPG)、空腹血糖(FPG)以及APACHEⅡ评分比较,差异无统计学意义(P>0.05)。治疗后,两组HbA1c、2 hPG、FPG均下降,且研究组低于比较组,差异有统计学意义(P<0.05)。治疗后,两组APACHEⅡ评分均下降,且研究组低于比较组,差异有统计学意义(P<0.05);研究组临床治疗总有效率高于比较组,差异有统计学意义(P<0.05)。研究组不良反应低于比较组,但差异无统计学意义(P>0.05)。结论左氧氟沙星联合胰岛素泵治疗2型糖尿病合并肺部感染效果良好,能有效降低患者血糖水平,提高治愈效果,降低APACHEⅡ评分,不良反应少。
Objective To investigate and analyze the effect of levofloxacin combined with insulin pump on the blood glucose level,Acute Physiological and Chronic HealthⅡ(APACHEⅡ)score of patients with type 2 diabetes mellitus combined with pulmonary infection.Methods 80 patients with diabetes and lung infection admitted to the intensive care Department of Macheng People's Hospital from September 2020 to September 2021 were selected as the research objects and divided into a comparison group(40 cases)and a study group(40 cases)using the random number table method.The comparison group received levofloxacin and conventional blood glucose control,and the study group used insulin pump therapy based on the comparison group.The treatment effects were compared in the two groups.Results Before treatment,compared the HbA1c(HbA1c),2 h postprandial blood glucose(2 hPG),fasting blood glucose(FPG),and APACHEⅡscore of two groups,the difference was not statistically significant(P>0.05).After treatment,HbA1c,2 hPG and FPG in the two groups decreased,and the study group was lower than the comparison group,the difference was statistically significant(P<0.05).After treatment,the APACHEⅡscores in the two groups decreased,and the study group was lower than the comparison group,the difference was statistically significant(P<0.05);the overall response rate of the study group was higher than the comparison group,the difference was statistically significant(P<0.05).The adverse effects in the study group were lower than those in the comparison group,but the difference was not statistically significant(P>0.05).Conclusion Levofloxacin combined with insulin pump is effective in the treatment of type 2 diabetes mellitus combined with pulmonary infection,which can effectively reduce patients'blood glucose level,improve the healing effect and reduce APACHE II score without increasing less adverse reactions.
作者
胡萌
毛长书
吴泽亨
HU Meng;MAO Changshu;WU Zeheng(Department of Critical Care Medicine,Macheng People's Hospital,Macheng,Hubei Province,438300 China)
出处
《糖尿病新世界》
2023年第5期54-58,共5页
Diabetes New World Magazine
关键词
肺部感染
左氧氟沙星
胰岛素泵
2型糖尿病
血糖水平
Pulmonary infection
Levofloxacin
Insulin pump
Type 2 diabetes mellitus
Blood glucose level
