摘要
慢性阻塞性肺疾病(COPD)是一种常见的呼吸系统疾病,而肺癌是COPD常见的合并症和主要死亡原因之一,两种疾病共存与较差的生存率有关。临床发现,COPD与肺癌的共病率高,属于同源性疾病,有共同的危险因素和发病机制,COPD可衍生肺癌发生的土壤。目前临床上对COPD与肺癌发病风险的关联已有许多认识,但对COPD合并肺癌患者的管理尚未达成共识,存在COPD诊断和治疗不足,从而影响此类患者的临床结局。因此,本文就近年COPD合并肺癌的流行病学现状、共同危险因素、相关发病机制及管理展开综述,以期为临床研究和治疗提供更多的理论基础和认识。
Chronic obstructive pulmonary disease(COPD)is a common respiratory disease,and lung cancer is a common comorbidity and one of the main causes of death in COPD.The coexistence of the two diseases is related to poor survival rate.Clinically,it has been found that COPD has a high comorbidity rate with lung cancer,belonging to a homologous disease with common risk factors and pathogenesis.COPD can be derived from the soil where lung cancer occurs.At present,there is much understanding of the association between COPD and the risk of lung cancer in clinical practice,but there is no consensus on the management of patients with COPD combined with lung cancer.There is insufficient diagnosis and treatment of COPD,which affects the clinical outcomes of such patients.Therefore,this article reviews the epidemiological status,common risk factors,related pathogenesis,and management of COPD combined with lung cancer in recent years,in order to provide more theoretical basis and understanding for clinical research and treatment.
作者
胡甜甜
薄建萍
Hu Tiantian;Bo Jianping(Department of Respiratory and Critical Care Medicine,the Second Hospital of Shanxi Medical University,Taiyuan 030000,China)
出处
《中国医师杂志》
CAS
2023年第5期798-800,F0003,共4页
Journal of Chinese Physician
关键词
肺疾病
慢性阻塞性
肺肿瘤
Pulmonary disease,chronic obstructive
Lung neoplasms
