摘要
术后胃肠道功能紊乱(postoperative gastrointestinal dysfunction,PGD)是手术患者最常见的并发症之一,临床表现为便秘、恶心呕吐,甚至通过脑肠轴影响认知功能等。PGD的中西医发病机制复杂,中医认为PGD与患者自身“本虚”和手术“外邪”侵扰有关。西医则认为手术创伤、炎症反应、胃肠激素水平紊乱、微生物菌群失衡等都可影响胃肠功能,进而造成PGD。该文就针刺改善PGD的调节炎症因子,改善胃肠道激素分泌,刺激迷走神经调节以及调节肠道菌群等多种机制进行总结说明,旨在为临床针刺干预PGD提供理论依据。
Postoperative gastrointestinal dysfunction(PGD)is one of the most common complications in surgical patients.Its clinical manifestations are constipation,nausea and vomiting,and even affect cognitive function through the brain gut axis.The mechanism of PGD in traditional Chinese medicine and Western medicine is complex.Traditional Chinese medicine believes that PGD is related to the patients'own“deficiency”and the invasion of“external pathogens”in surgery.Western medicine believes that surgical trauma,inflammatory reaction,gastrointestinal hormone level disorder,microbial flora imbalance can affect gastrointestinal function,resulting in PGD.This paper summarizes the mechanisms of acupuncture improving PGD,such as regulating inflammatory factors,improving gastrointestinal hormone secretion,stimulating vagus nerve regulation and regulating intestinal flora,in order to provide a theoretical basis for acupuncture intervention in PGD in clinic.
作者
李玉才
王群
张维亮
迟永良
田晨羲
刘慧
LI Yucai;WANG Qun;ZHANG Weiliang;CHI Yongliang;TIAN Chenxi;LIU Hui(Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong,China)
出处
《辽宁中医药大学学报》
CAS
2023年第5期107-112,共6页
Journal of Liaoning University of Traditional Chinese Medicine
基金
山东省自然科学基金面上项目(ZR2021MH168)
山东省中医药科技发展计划项目(2019—0176)。
关键词
针刺
围术期
胃肠道功能紊乱
保护机制
acupuncture
perioperative period
postoperative gastrointestinal gysfunction
protection mechanism
