摘要
目的:探讨B族链球菌感染对孕晚期高危妊娠孕妇的母婴结局影响。方法:选择2019年6月-2022年12月本院收治的孕晚期高危妊娠孕妇130例,其中高危合并GBS感染组(高危GBS组)65例,高危未GBS感染组(高危组)65例;同期正常妊娠孕妇130例为对照组。对各组一般资料、妊娠结局及新生儿并发症情况进行比较分析。结果:对照组、高危组、高危GBS组胎膜早破(3.1%、13.9%、32.3%)、产后出血(0.8%、3.1%、9.2%)、羊水污染(2.3%、10.8%、24.6%)、剖宫产(14.6%、40.0%、56.9%)、产褥感染(0、15.4%、23.1%)等不良妊娠结局发生率依次增加,新生儿宫内窘迫(4.6%、20.0%、27.7%)、败血症(0、7.7%、12.3%)、新生儿黄疸(9.2%、29.2%、41.5%)、新生儿肺炎(1.5%、10.8%、16.9%)和新生儿窒息(3.1%、15.4%、21.5%)等新生儿并发症发生率依次升高(均P<0.05)。结论:高危妊娠孕妇母婴不良妊娠结局风险较高,而合并GBS感染会增加母婴不良妊娠结局风险,需重视对高危妊娠孕妇围产期GBS筛查以及预防性治疗。
Objective:To explore the impact of group B streptococcus(GBS)infection of pregnant women with high risk factors during the third trimester of pregnancy on their maternal and infant outcomes.Methods:13pregnant women with high risk factors during the third trimester of pregnancy were selected in study group from June 2019to December 2022,including 65cases with GBS infection in group A and 65cases=T-without GBS infection in group B.Another 130normal pregnant women were selected in control group during the same period.The general information,the pregnancy outcomes,and the neonatal complications of the women were compared and analyzed among these groups.Results:The incidences of adverse pregnancy outcomes,such as premature rupture of membranes(3.1%,13.9%,and 32.3%),the postpartum hemorrhage(0.8%,3.1%,and 9.2%),the amniotic fluid pollution(2.3%,10.8%,and 24.6%),the caesarean section(14.6%,40.0%,and 56.9%),and the puerperal infection(0,15.4%,and 23.1%),of the women in the control group,in the study group,and in the group A had increased gradually,and the incidences of the neonatal intrauterine distress(4.6%,20.0%,and 27.7%),septicemia(0,7.7%,and 12.3%),jaundice(9.2%,29.2%,and 41.5%),pneumonia(1.5%,10.8%,and 16.9%),and asphyxia(3.1%,15.4%,and 21.5%)in the control group,in the study group,and in the group A had also increased gradually(all P<0.05).Conclusion:The pregnant women with high risk factors have higher risk of adverse pregnancy outcomes.The high risk factors of the pregnant women and their GBS infection all can increase the risk of their adverse pregnancy outcomes.Therefore,it is necessary to pay attention to the perinatal GBS screening and to the preventive treatment for the pregnant women with high risk factors.
作者
黄金瑞
梁海峰
黄玲玲
HUANG Jinrui;LIANG Haifeng;HUANG Lingling(Guangxi Medical University Kaiyuan Hospital,Nanning,Guangxi,530000;Guangxi Hospital of Qianhai Life Insurance,Nanning;Cancer Hospital Affiliated to Guangxi Medical University,Nanning)
出处
《中国计划生育学杂志》
2023年第6期1474-1477,共4页
Chinese Journal of Family Planning
基金
广西壮族自治区卫生健康委员会自筹经费科研项目(Z20190714)。
关键词
高危妊娠
妊娠晚期
B族链球菌
不良妊娠结局
不良新生儿结局
High-risk pregnancy
Third trimester of pregnancy
Group B streptococcus
Adverse pregnancy outcomes
Adverse neonatal outcomes
