摘要
目的探讨影响类风湿关节炎患者并发肺部感染的相关危险因素。方法选取2019年1月—2022年1月黑龙江省大庆龙南医院收治的类风湿关节炎患者270例进行回顾性分析,将30例发生肺部感染和240例未发生肺部感染的患者分别纳入发生肺部感染组和未发生肺部感染组。单因素分析两组患者的临床一般资料,多因素分析其中差异有统计学意义的因素,筛选出相关危险因素。结果单因素及多因素分析结果显示,年龄、病程、吸烟、合并间质性肺炎、应用糖皮质激素、应用抗菌药物、合并2型糖尿病、疾病活动性指数、低血清RF水平均为类风湿关节炎患者并发肺部感染的独立危险因素(OR=2.061、1.952、1.910、2.046、1.818、1.923、1.885、1.870、1.756,P<0.05)。结论针对年龄、病程、吸烟、合并间质性肺炎、应用糖皮质激素、应用抗菌药物、合并2型糖尿病、疾病活动性指数、低血清RF水平这些独立危险因素,临床上应依此采取相应的预防措施,减少肺部感染的发生,改善预后。
Objective To explore the risk factors associated with pulmonary infections affecting patients with rheumatoid arthritis.Methods Two hundred and seventy rheumatoid arthritis patients admitted to Daqing Longnan Hospital from January 2019 to January 2022 were selected for retrospective analysis.The 30 patients with pulmonary infection and 240 patients without develop pulmonary infection were included the group with pulmonary infection and the group without develop pulmonary infection,respectively.Single-factor analysis was performed to analyze the general clinical data of the two groups,and multifactor analysis was performed to screen out the relevant risk factors in which the differences were statistically significant.Results Univariate and multifactorial analyses showed that age,disease duration,smoking,combined interstitial pneumonia,application of glucocorticoids,application of antibacterial drugs,combined type 2 diabetes,disease activity index,and low serum RF level were independent risk factors for pulmonary infection in patients with rheumatoid arthritis(OR=2.061,1.952,1.910,2.046,1.818,1.923,1.885,1.870,1.756,P<0.05).Conclusion For independent risk factors of age,disease duration,smoking,combined interstitial pneumonia,corticosteroids,antimicrobial application,combined type 2 diabetes,disease activity index,and low serum RF level,clinical preventive measures should be taken accordingly to reduce the occurrence of pulmonary infections and improve the prognosis.
作者
杨巍巍
YANG Weiwei(Department of Laboratory,Daqing Longnan Hospital,Daqing,Heilongjiang Province,163458 China)
出处
《系统医学》
2023年第4期72-75,共4页
Systems Medicine
关键词
类风湿关节炎
肺部感染
危险因素
Rheumatoid arthritis
Pulmonary infection
Risk factors
