摘要
目的:探讨丙泊酚复合瑞芬太尼静脉麻醉在老年腹腔镜胆囊切除术患者中的应用效果。方法:选取2021年4月—2022年10月于徐州市贾汪区人民医院行腹腔镜胆囊切除术的80例老年患者作为研究对象,根据随机数字表法分为观察组和对照组,各40例。两组患者均采用气管插管全身麻醉,并实施静脉快速诱导,观察组给予丙泊酚复合瑞芬太尼持续泵注维持麻醉,对照组给予七氟醚吸入复合瑞芬太尼持续泵注维持麻醉。比较两组麻醉效果。结果:观察组自主呼吸恢复时间、拔管时间、苏醒时间、定向力恢复时间均短于对照组,差异有统计学意义(P<0.001)。观察组不良反应发生率低于对照组,差异有统计学意义(P<0.001)。术后1、4、12h,观察组简易智力状态检查量表评分高于对照组,差异有统计学意义(P<0.001)。两组术后1、4、12、24、48 h疼痛评分比较,差异无统计学意义(P>0.05)。结论:老年腹腔镜胆囊切除术患者麻醉维持采用丙泊酚复合瑞芬太尼,麻醉效果显著,术后苏醒快,不良反应少,对认知功能影响小。
Objective:To investigate the application effect of propofol and remifentanil intravenous anesthesia in elderly patients undergoing laparoscopic cholecystectomy.Methods:A total of 80 elderly patients who underwent laparoscopic cholecystectomy in the People's Hospital of Jiawang District of Xuzhou from April 2021 to October 2022 were selected as the study subjects.They were divided into the observation group and the control group according to random number table method,with 40 patients in each group.Both groups were given general anesthesia by endotracheal intubation and were given rapid intravenous induction.The observation group was given continuous pumping of propofol combined with remifentanil for anesthesia maintenance,while the control group was given of sevoflurane inhalation combined with remifentanil continuous pumping for anesthesia maintenance.The anesthesia effect in two groups was compared.Results:The time of spontaneous respiration recovery,extubation time,wake time and time of orientation recovery in the observation group were shorter than those in the control group,and the difference was statistically significant(P<0.001).The incidence of adverse reactions in the observation group was lower than that of the control group,and the difference was significant(P<0.001).At 1 h,4 h and 12 h after surgery,the scores of Mini-Mental State Examination in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.001).At 1 h,4 h,12 h,24 h and 48 h after surgery,there was no statistically significant difference in the pain scores between the two groups(P>0.05).Conclusion:The application of propofol combined with remifentanil for anesthesia maintenance in elderly patients with laparoscopic cholecystectomy has significant anesthesia effect,fast postoperative recovery,few adverse reactions and few influence on cognitive function.
作者
朱芳
Zhu Fang(Department of Anesthesiology,The People's Hospital of Jiawang District of Xuzhou,Xuzhou 221011,Jiangsu Province,China)
出处
《中国社区医师》
2023年第17期16-18,共3页
Chinese Community Doctors
关键词
七氟醚
丙泊酚
麻醉
老年人
腹腔镜胆囊切除术
Sevoflurane
Propofol
Anesthesia
Elderly
Laparoscopic cholecystectomy
