摘要
目的 探讨无创呼吸机使用者医院感染的现状及其发生的危险因素,为无创呼吸机医院感染控制提供科学依据。方法 对2021年1月—2022年12月入院的无创呼吸机使用者进行调查,分析无创呼吸机使用者发生医院感染的易感因素。结果 共纳入无创呼吸机使用者419例,发生下呼吸道感染53例,感染率12.7%。感染组与对照组的呼吸机类型分布不同,差异有统计学意义(P<0.05),感染组中高频喷射呼吸机使用者较多。从感染组患者中检出菌株41株,检出菌前4位为铜绿假单胞菌10株、肺炎克雷伯菌7株、鲍曼不动杆菌6株、白色念珠菌5株。不同住院天数、转科、手术、曾住ICU、联用抗菌药物的无创呼吸机使用者的医院感染率差异有统计学意义(P<0.05);住院天数>15 d (OR=15.875,95%CI:2.020~124.759)和手术(OR=2.342,95%CI:1.161~4.724)是无创呼吸机使用者发生下呼吸道医院感染的独立危险因素。结论 无创呼吸机使用者医院感染率较高,感染组患者中检出菌以革兰阴性杆菌为主,住院天数>15 d和手术是主要危险因素。
Objective To explore the prevalence and influencing factors of non-invasive ventilation associated nosocomial infection,and to provide evidence for nosocomial infection control.Methods The clinical data of in-patients form Jan.2021 to Dec.2022 were analyzed for the influencing factors of nosocomial infections among non-invasive ventilation users.Results A total of 53(12.7%)cases were diagnosed as lower respiratory tract infection among 419in-patients using non-invasive ventilation.Compared with control group,there were more high frequency jet ventilation users in infection group(P0.05).41 strains of pathogens were isolated in the infection group,the top 4detected were Pseudomonas aeruginosa(10 strains),Klebsiella pneumonia(7 strains),Acinetobacter baumaannii(6strains)and Andida albicans(5 strains).The incidence of nosocomial infection among non-invasive ventilation users differed significantly by hospital stay,transfer wards,surgery operation,combined antimicrobial,ICU stay(P 0.05).Surgery(OR=15.875,95%CI:2.020-124.759)and hospital stay 15 d(OR=2.342,95%CI:1.161-4.724)were the independent risk factors of nosocomial infection among non-invasive ventilation users.Conclusion The non-invasive ventilation users had a relatively higher incidence of nosocomial infection.The Gram-negative bacteria was major bacteria in infected group.Surgery and hospital stay 15 d were the major influencing factors of nosocomial infection among non-invasive ventilation users.
作者
吴逸海
陈夏容
林丽玲
曾秀玉
张华平
陈卢峰
邱秀兰
翁月萍
张贻浓
WU Yihai;CHEN Xiarong;LIN Liling;ZENG Xiuyu;ZHANG Huaping;CHEN Lufeng;QIU Xiulan;WENG Yueping;ZHANG Yinong(Hospital Acquired Infection Control Department,the Second Afiliaed Hospital of Fujian Medical University,Quanzhou,Fujian 362000,China)
出处
《中国国境卫生检疫杂志》
CAS
2023年第4期352-355,共4页
Chinese Journal of Frontier Health and Quarantine
基金
福建省中青年教师教育科研项目(JAT210099)。
关键词
无创呼吸机
危险因素
医院感染
No-invasive ventilation
Risk factor
Nosocomial infection
