摘要
目的分析常规检验和生化检验对糖尿病的诊断价值。方法选择2020年1月—2022年1月在东营市利津县明集中心卫生院就诊的70例疑似糖尿病患者作为研究对象,分别进行常规检验和生化检验(检测指标为空腹血糖、餐后2 h血糖、糖化血红蛋白、糖耐量、总胆固醇、三酰甘油),比较两种检验方法的结果和对糖尿病的诊断效能。结果70例患者给予“金标准”诊断后,其中60例确诊为糖尿病;常规检验的敏感度、特异度、准确度分别为83.33%、70.00%、81.43%,生化检验的敏感度、特异度、准确度分别为96.67%、60.00%、91.43%,生化检验的敏感度和准确度均明显高于常规检验(均P<0.05),两种方式的特异度比较差异无统计学意义(P>0.05)。对两种检验方法的血糖指标水平进行比较,结果表明生化检验所得的空腹血糖、餐后2 h血糖、糖化血红蛋白、糖耐量、总胆固醇、三酰甘油水平均高于常规检验,但差异均无统计学意义[空腹血糖(mmol/L):7.42±1.36比7.06±1.25,餐后2 h血糖(mmol/L):8.75±1.25比8.40±1.33,糖化血红蛋白:0.074±0.012比0.072±0.010,糖耐量(mmol/L):8.03±1.33比7.60±1.45,总胆固醇(mmol/L):1.30±0.35比1.21±0.25,三酰甘油(mmol/L):6.89±1.35比6.55±1.02,均P>0.05]。结论对糖尿病患者加强生化检验有助于保证较高的诊断效能,为疾病诊断提供科学依据。
Objective To analyze the diagnostic value of routine test and biochemical test in diabetes mellitus.Methods From January 2020 to January 2022,70 patients with suspected diabetes mellitus admitted to Dongying Lijin County Mingji Center Health Center were selected as research objects.Routine and biochemical tests were performed respectively(detection indexes were fasting blood glucose,2 hours postmeal blood glucose,glycated hemoglobin,glucose tolerance,total cholesterol and triacylglycerol).The results and diagnostic efficacies of the two methods were compared.Results After the"gold standard"diagnosis of 70 patients,60 of them were diagnosed as diabetes mellitus.The sensitivity,specificity and accuracy of routine test were 83.33%,70.00%and 81.43%,respectively,and the sensitivity,specificity and accuracy of biochemical test were 96.67%,60.00%and 91.43%,respectively.The sensitivity and accuracy of biochemical test were significantly higher than those of conventional test(both P<0.05).There was no statistical significance in the comparison of specificity between the two methods(P>0.05).By comparing the blood glucose index levels of the two test methods,it was known that in the biochemical test,the levels of fasting blood glucose,2 hour postprandional blood glucose,glycated hemoglobin,glucose tolerance,total cholesterol and triacylglycerol were higher than those by routine tests,but the differences were not statistically significant[fasting blood glucose(mmol/L):7.42±1.36 vs.7.06±1.25,2 hour postprandional blood glucose(mmol/L):8.75±1.25 vs.8.40±1.33,glycated hemoglobin:0.074±0.012 vs.0.072±0.010,glucose tolerance(mmol/L):8.03±1.33 vs.7.60±1.45,total cholesterol(mmol/L):1.30±0.35 vs.1.21±0.25,triacylglycerol(mmol/L):6.89±1.35 vs.6.55±1.02,all P>0.05].Conclusion Strengthening biochemical test for patients with diabetes mellitus is helpful to ensure higher diagnostic efficiency and provide scientific basis for disease diagnosis.
作者
刘芳芳
王曙光
Liu Fangfang;Wang Shuguang(Department of Clinical Laboratory,Dongying Lijin County Mingji Center Health Center,Dongying 257442,Shandong,China;Department of Clinical Laboratory,Dongying Lijin County Beisong Health Center,Dongying 257439,Shandong,China)
出处
《实用检验医师杂志》
2023年第2期151-154,共4页
Chinese Journal of Clinical Pathologist
关键词
糖尿病
常规检验
生化检验
Diabetes mellitus
Routine test
Biochemical test
