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血常规检验和血脂检验在脂肪肝患儿的临床实施价值研究

Study on the Clinical Implementation Value of Routine Blood Tests and Lipid Tests in Children with Fatty Liver Disease
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摘要 目的探究血常规检验和血脂检验在脂肪肝患儿中的临床实施价值。方法选择2020年1月—2022年12月将巨野县人民医院收治的60例脂肪肝患儿作为观察组,将同期参与体检的60例正常儿童作为对照组,均实施血常规检验和血脂检验,统计两组血常规检验和血脂检验结果。结果观察组血常规指标中红细胞、白细胞、血红蛋白、单核细胞计数均明显高于对照组,血小板低于对照组,差异有统计学意义(P<0.05)。观察组三酰甘油、血清总胆固醇、低密度脂蛋白、尿酸均高于对照组,高密度脂蛋白低于对照组,差异有统计学意义(P<0.05)。不同分级脂肪肝和红细胞、白细胞、单核细胞计数、血红蛋白呈正相关(r=0.894、0.926、0.891、0.932,P=0.008、0.002、0.008、0.001),和血小板呈负相关(r=-0.874,P=0.012)。不同分级脂肪肝和血清总胆固醇、低密度脂蛋白、三酰甘油、尿酸呈正相关(r=0.754、0.901、0.912、0.907,P=0.010、0.003、0.004、0.002),和高密度脂蛋白呈负相关(r=-0.917,P=0.003)。结论脂肪肝患儿血常规检验和血脂检验相关指标均存在明显异常,且疾病越严重,血常规、血脂指标异常情况越明显,在临床治疗中,需要重视调节血脂、血常规指标,并加强这些指标的监测,从而随时调整治疗方案,促使患儿尽早恢复健康。 Objective To investigate the clinical implementation value of routine blood tests and lipid tests in children with fatty liver.Methods From January 2020 to December 2022,60 children with fatty liver admitted to Juye County People's Hospital were selected as the observation group,and 60 normal children who participated in the physical examination during the same period were selected as the control group.Blood routine test and blood lipid test were performed,and the results of blood routine test and blood lipid test in the two groups were counted.Results The blood routine indexes of red blood cells,white blood cells and hemoglobin,monocyte count in the observation group were significantly higher than those in the control group,and the platelets were lower than those in the control group,the differences were statistically significant(P<0.05).The triglyceride,serum total cholesterol,low density lipoprotein and uric acid in the observation group were higher than those in the control group,and the high density lipoprotein was lower than that in the control group,the differences were statistically significant(P<0.05).Different grades of fatty liver were positively correlated with red blood cells,white blood cells,monocyte counts,and hemoglobin(r=0.894,0.926,0.891,0.932,P=0.008,0.002,0.008,0.001),and negatively correlated with platelets(r=-0.874,P=0.012).Different grades of fatty liver were positively correlated with serum total cholesterol,low density lipoprotein,triglyceride and uric acid(r=0.754,0.901,0.912,0.907,P=0.010,0.003,0.004,0.002),and negatively correlated with high density lipoprotein(r=-0.917,P=0.003).Conclusion Children with fatty liver have obvious abnormalities in routine blood tests and lipid test related indexes,and the more serious the disease,the more obvious abnormalities in routine blood and lipid indexes.In clinical treatment,it is necessary to pay attention to the regulation of blood lipids and blood routine indexes,and strengthen the monitoring of these indexes,so as to adjust the treatment program at any time,and promote the early recovery of children's health.
作者 吴霜 谢秀菊 国凤桂 WU Shuang;XIE Xiuju;GUO Fenggui(Department of Laboratory,Juye County People's Hospital,Heze,Shandong Province,274900 China)
出处 《系统医学》 2023年第15期162-165,共4页 Systems Medicine
关键词 血常规检验 血脂检验 脂肪肝 Routine blood test Lipid test Fatty liver
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