摘要
[目的]分析2010—2018年淮安市食管癌发病率、死亡率及早死疾病负担趋势。[方法]将淮安市肿瘤登记上报的2010—2018年食管癌发病及死亡数据,按照性别、年龄分层计算食管癌粗发病(死亡)率和标化发病(死亡)率。计算早死寿命损失年(years of life lost,YLL)、YLL率和人均寿命损失年(average years of life lost,AYLL)。食管癌发病、死亡及早死疾病负担变化趋势采用年度变化百分比(annual percentage change,APC)进行分析。[结果]2010—2018年食管癌粗发病率为59.09/10万,男性(71.64/10万)粗发病率高于女性(45.94/10万);粗死亡率为43.50/10万,男性粗死亡率(52.79/10万)高于女性(33.76/10万)。食管癌男性、女性、合计人群标化发病率APC分别为-4.11%、-4.66%和-4.23%,标化死亡率APC分别为-2.03%、-3.02%和-2.39%,均呈明显下降趋势(P均<0.05)。<50岁、50~59岁、60~69岁年龄组食管癌粗发病率APC分别为-13.11%、-11.68%和-4.05%,粗死亡率APC分别为-15.22%、-12.28%和-3.53%,均呈逐年下降趋势(P均<0.05);≥70岁组食管癌粗死亡率APC为1.69%,呈上升趋势(P<0.05)。淮安市居民女性和合计人群食管癌的YLL率APC分别为-1.91%、-1.45%,均呈逐年下降趋势(P均<0.05);男性、女性和合计人群AYLL的APC分别为-2.68%、-3.03%、-2.71%,均呈逐年下降趋势(P均<0.05)。[结论]2010—2018年淮安市食管癌发病、死亡及早死疾病负担均呈下降趋势,男性和老年人是食管癌重点防治人群。
[Purpose]To analyze the trends of incidence,mortality and disease burden of esophageal cancer in Huai’an City from 2010 to 2018.[Methods]The crude incidence/mortality rats and age-standardized incidence/mortality rates(ASIR/ASMR)were calculated by gender and age.The years of life lost(YLL),YLL rate and average years of life lost per 1000(AYLL)were also calculated,and the annual percentage change(APC)was used to analyze the disease burden of esophageal cancer.[Results]From 2010 to 2018,the crude incidence rate of esophageal cancer was 59.09/105,and the crude incidence rate in male(71.64/105)was higher than that in female(45.94/105).The crude mortality rate was 43.50/105,and the crude mortality rate in male(52.79/105)was higher than that in female(33.76/105).The APC of ASIR and ASMR of esophageal cancer for male,female and total population were-4.11%,-4.66%,-4.23%;and-2.03%,-3.02%,-2.39%,respectively,showing a significant downward trend(all P<0.05).The APC of crude incidence and mortality rates in the age groups of<50,50~59,60~69 years old were-13.11%,-11.68%,-4.05%;and-15.22%,-12.28%and-3.53%,respectively,showing a decreasing trends(all P<0.05);while the APC of crude esophageal cancer in the age group of>70 years old was 1.69%,showing an increasing trend(P<0.05).The APC of YLL in female and total population were-1.91%and-1.45%,respectively,showing a decreasing trend(P<0.05);and the APC of AYLL in male,female and total population was-2.68%,-3.03%and-2.71%,respectively,showing a decreasing trend(all P<0.05).[Conclusion]From 2010 to 2018,the incidence,mortality and disease burden of esophageal cancer in Huai’an City showed a downward trend.Male and elderly people are the key groups of prevention and treatment of esophageal cancer.
作者
庞荣焕
孙中明
缪丹丹
沈欢
文进博
梅冬蒙
刘景
赵倩
潘恩春
PANG Ronghuan;SUN Zhongming;MIAO Dandan;SHEN Huan;WEN Jinbo;MEI Dongmeng;LIU Jing;ZHAO Qian;PAN Enchun(School of Public Health,Xuzhou Medical University,Xuzhou 221004,China;Huai'an Center for Disease Control and Prevention,Huai'an 223001,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2023年第9期691-697,共7页
China Cancer
基金
江苏省第五期“333工程”科研资助立项项目(BRA2017242)。
关键词
食管癌
发病率
死亡率
早死寿命损失年
疾病负担
趋势分析
江苏
esophageal cancer
incidence
mortality
years of life lost
burden of disease
trend analysis
Jiangsu
