摘要
目的 探讨癫痫患者血清尿酸和神经元特异性烯醇化酶(NSE)水平的变化及临床意义。方法 检测116例癫痫患者(病例组)及116例健康成人(对照组)的尿酸和NSE水平。根据发作特点将病例组分为抽搐组(72例)、非抽搐组(44例)以及频发组(70例)、非频发组(46例),分别比较各组尿酸和NSE水平。结果 各组血清尿酸和NSE水平比较:病例组高于对照组,抽搐组高于非抽搐组,频发组高于非频发组(均P<0.01)。结论 癫痫患者血清尿酸和NSE水平显著高于对照组,且尿酸和NSE在不同类型的癫痫患者中存在差异。
Objective To observe the changes in serum uric acid and neuron-specific enolase(NSE) level in epilepsy patients and the clinical significance thereof.Methods The levels of uric acid and NSE of 116 epilepsy patients(Case Group)and 116 healthy adults(Control Group) were detected.According to the characteristics of onset,the Case Group was further divided into a Convulsive Group(72 cases) and a Non-Convulsive Group(44 cases),and a Frequent Group(70 cases) and a Non-Frequent Group(46 cases).The levels of uric acid and NSE in each group were compared.Results For the comparison of serum uric acid and NSE levels among the groups,the Case Group was higher than the Control Group,the Convulsive Group was higher than the Non-Convulsive Group,and the Frequent Group was higher than the Non-Frequent Group(P<0.01 for all).Conclusion The serum uric acid and NSE levels in epilepsy patients were significantly higher than those in the healthy control group,and there were differences in uric acid and NSE levels among different types of epilepsy patients.
作者
梁维
潘剑罡
廖志敏
金聪丽
LIANG Wei;PAN Jian-gang;LIAO Zhi-min;JIN Cong-li(Department of Neurology,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,China)
出处
《广东医科大学学报》
2023年第5期556-558,共3页
Journal of Guangdong Medical University
基金
广东医科大学科研基金项目(GDMUM2019017)
湛江市科技项目(2020B01129)。
