摘要
血管性痴呆是脑血管病变后所引起的认知功能障碍,是临床中较为常见的痴呆类型。其发病机制源于血管系统损害引起低脑血流灌注、氧化应激等一系列病理过程。针灸作为一种非药物疗法,在脑血管病及相关疾病中有较为广泛的临床应用,许多研究都显示了针灸对认知功能的改善作用,并涉及细胞凋亡、氧化应激、神经炎症、神经递质通路等方面的调节作用。因此,现从血管性痴呆的发病机制角度探讨针刺的治疗作用,以期为进一步揭示针灸在血管性痴呆治疗中的潜在机制提供参考。
Vascular dementia is a cognitive impairment caused by cerebrovascular diseases and a common type of dementia in clinical practice.This disease stems from a series of pathological processes such as low cerebral blood flow perfusion and oxidative stress caused by vascular system damage.As a non-drug therapy,acupuncture and moxibustion has a wide application range in the clinical treatment of cerebrovascular diseases and related diseases.Studies have shown that acupuncture and moxibustion can improve cognitive function,which involves the regulation of cell apoptosis,oxidative stress,neuroinflammation,and neurotransmitter pathway.Therefore,this paper introduces the therapeutic effect of acupuncture from the pathogenesis of vascular dementia,aiming to provide a reference for further revealing the potential mechanism of acupuncture in the treatment of vascular dementia.
作者
陆佳婧
侯瑜超
黄思维
李璟
王文佳
LU Jiajing;HOU Yuchao;HUANG Siwei;LI Jing;WANG Wenjia(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)
出处
《世界中医药》
CAS
2023年第17期2556-2559,2564,共5页
World Chinese Medicine
基金
上海市临床重点专科建设项目(shslczdzk04701)
上海市针灸临床医学研究中心(20MC1920500)。
关键词
针刺治疗
血管性痴呆
认知功能障碍
氧化应激
神经炎症
神经递质通路
神经修复
综述
Acupuncture treatment
Vascular dementia
Cognitive impairment
Oxidative stress
Neuroinflammation
Neurotransmitter pathway
Nerve repair
Review
