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经皮椎体成形术与经皮椎体后凸成形术治疗骨质疏松椎体压缩性骨折的临床疗效比较

Clinical Effect of Percutaneous Vertebroplasty and Percutaneous Kyphoplasty on Osteoporotic Vertebral Compression Fracture
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摘要 目的探究经皮椎体成形术(PVP)与经皮椎体后凸成形术(PKP)对骨质疏松椎体压缩性骨折(OVCF)的临床治疗效果。方法选取2018年1月至2020年10月在阆中市人民医院行手术治疗的180例OVCF患者,按手术方式分为PVP组(90例)和PKP组(90例)。比较两组患者一般临床资料、围手术期指标、手术前后疼痛视觉模拟评分法(VAS)评分、Oswestry功能障碍指数(ODI)、病变椎体前缘高度比及Cobb角、术后并发症发生情况。结果两组患者性别、年龄、体质量指数、骨密度值比较差异无统计学意义(P>0.05)。PKP组手术时间、术后住院时间均长于PVP组[(52±5)min比(34±7)min、(6.1±1.8)d比(3.5±1.0)d](P<0.05),且骨水泥注入量多于PVP组[(5.12±0.33)ml比(3.04±0.35)ml](P<0.05),但两组X线曝光次数比较差异无统计学意义(P>0.05)。手术前后VAS评分、ODI以及椎体前缘高度及Cobb角的主效应差异有统计学意义(P<0.01);不考虑测量时间,两组间VAS评分、ODI、椎体前缘高度及Cobb角的主效应差异有统计学意义(P<0.05或P<0.01);VAS评分、ODI、椎体前缘高度及Cobb角的组间与时点间存在交互作用(P<0.05或P<0.01),且PKP组变化更明显(P<0.05)。PKP组患者术后并发症发生率明显低于PVP组为[10.00%(9/90)比33.33%(30/90)](P<0.01)。结论PVP、PKP均可有效缓解OVCF患者疼痛,PKP术后并发症发生率较低,而PVP在手术时间、住院时间、住院费用等方面优于PKP。 Objective To investigate the clinical effect of percutaneous vertebroplasty(PVP)and percutaneous kyphoplasty(PKP)on osteoporotic vertebral compression fracture(OVCF).Methods A total of 180 OVCF patients who underwent surgical treatment in Langzhong People′s Hospital from Jan.2018 to Oct.2020 were selected and divided into a PVP group(90 cases)and a PKP group(90 cases)according to the surgical method.The general clinical data,perioperative indicators,visual analogue scale(VAS)score of pain before and after surgery,Oswestry disability index(ODI),anterior height ratio of lesion vertebral body and Cobb angle were compared between the two groups,as well as the postoperative complications.Results There was no significant difference in gender,age,body mass index and bone mineral density between the two groups(P>0.05).The operation time,and postoperative hospital stay in the PKP group were longer than those in the PVP group[(52±5)min vs(34±7)min,(6.1±1.8)d vs(3.5±1.0)d](P<0.05),the amount of bone cement injected was more than that in the PVP group[(5.12±0.33)ml vs(3.04±0.35)ml](P<0.05),and there was no significant difference in the number of X-ray exposures between the two groups(P>0.05).There were significant differences in the main effects of VAS score,ODI,anterior vertebral body height and Cobb angle before and after surgery(P<0.01);regardless of the measurement time,there were significant differences in the main effects of VAS score and ODI,anterior vertebral height and Cobb angle between the two groups(P<0.05 or P<0.01);there were interactions in VAS score,ODI,anterior vertebral height and Cobb angle between time points and groups(P<0.05 or P<0.01),and the changes were more obvious in the PKP group(P<0.05).The incidence of postoperative complications in the PKP group was significantly lower than that in the PVP group[10.00%(9/90)vs 33.33%(30/90)](P<0.01).Conclusion Both PVP and PKP can effectively relieve pain in OVCF patients,and the incidence of complications after PKP is lower,while PVP is superior to PKP in terms of operation time,hospitalization time,and hospitalization costs.
作者 田龙 胡萌 吴晓荣 吕国荣 TIAN Long;HU Meng;WU Xiaorong;LYU Guorong(Department of Orthopedics,Langzhong People′s Hospital,Langzhong 637400,China)
出处 《医学综述》 CAS 2022年第23期4781-4784,F0003,共5页 Medical Recapitulate
关键词 骨质疏松椎体压缩性骨折 经皮椎体成形术 经皮椎体后凸成形术 Osteoporotic vertebral compression fracture Percutaneous vertebroplasty Percutaneous kyphoplasty
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