摘要
2型糖尿病(T2DM)作为一种常见的慢性代谢性疾病,其发病机制可能与肠道菌群失调相关。目前基于肠道菌群这一靶点,应用运动改善肠道菌群治疗T2DM具有独特且明显的优势,通过改善肠道内菌群紊乱可有效降低T2DM的发病率。运动是一种能够调节肠道菌群数量和结构的稳态刺激因素,可改善能量代谢、调节氧化应激、降低机体炎症等,达到防治2型糖尿病的目的,并可能为未来预防治疗一系列代谢性疾病提供新的方法和治疗策略。
Type 2 diabetes mellitus(T2DM)is a common chronic metabolic disease,and its pathogenesis may be related to the imbalance of gut microbiota.At present,based on the target of gut microbiota,the application of exercise to improve gut microbiota has unique and obvious advantages in treating T2DM,and the incidence of T2DM can be effectively reduced by improving the intestinal flora disorder.Exercise is a stable stimulus that can adjust the number and structure of gut microbiota,improve energy metabolism,regulate oxidative stress,and reduce body inflammation,achieving the purpose of preventing and treating T2DM,which may provide new methods and treatment strategies for the prevention and treatment of a series of metabolic diseases in the future.
作者
李炳瑶
吴民民
王雪
王琪
朱路文
LI Bingyao;WU Minmin;WANG Xue;WANG Qi;ZHU Luwen(Heilongjiang University of Chinese Medicine,Harbin 150006,China;the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《医学综述》
CAS
2023年第19期3897-3902,共6页
Medical Recapitulate
基金
国家重点研发计划(2019YFC1710301)。
关键词
糖尿病
2型
肠道菌群
运动
Diabetes mellitus,type 2
Gut microbiota
Exercise
