摘要
目的探讨经阴道超声联合弹性成像技术在宫腔病变鉴别中的价值。方法选取2018年1月—2021年1月于河北北方学院附属第二医院妇科就诊的宫腔病变患者126例,使用GE-E10彩色多普勒超声诊断仪进行经阴道超声和经阴道弹性成像检查,探头频率5~9 MHz,以组织病理学检查结果为“金标准”,分别比较经阴道超声、弹性成像及联合检查的结果,同时记录病变宫腔组织的平均弹性值(Emea)、最大弹性值(Emax)、最小弹性值(Emin)、弹性值标准差(Esd),比较良恶性宫腔病变的弹性模量值差异,绘制各弹性模量值诊断宫腔良恶性病变的受试者工作特征曲线(ROC),分析阴道超声联合弹性成像在宫腔良恶性病变鉴别诊断中的应用价值。结果恶性病变组弹性成像的Emea、Emax、Emin及Esd均高于良性病变组,差异具有统计学意义(t=28.573、23.996、2.618、17.412,P均<0.01);经阴道超声检查恶性病变与组织病理学确诊的符合率为54.3%,弹性成像检查为71.4%,联合检查为88.6%;经阴道超声检查良性病变与组织病理学确诊的符合率为82.1%,弹性成像检查为78.6%,联合检查为92.9%。经阴道超声检查诊断良恶性病变AUC为0.538,弹性成像技术AUC为0.661,联合检查AUC为0.788,联合检查AUC高于经阴道超声检查、弹性成像技术(P=0.04)。结论经阴道超声联合超声弹性成像技术可提高宫腔恶性病变的诊断准确率。
Objective To explore the value of transvaginal ultrasound combined with elastography in the differentiation of uterine cavity lesions.Methods One hundred and twenty-six patients with uterine cavity lesions who were treated in the Gynecology Department of the Second Affiliated Hospital of Hebei North University from January 2018 to January 2021 were selected for transvaginal ultrasound and transvaginal elastography using the GE-E10 color Doppler ultrasound diagnostic instrument.The probe frequency was 5-9 MHz,and the histopathological examination results were used as the"gold standard"to compare the results of transvaginal ultrasound,elastography,and combined examination,respectively,Simultaneously record the average elastic value(Emea),maximum elastic value(Emax),minimum elastic value(Emin),and standard deviation of elasticity(Esd)of the diseased uterine cavity tissue,compare the differences in elastic modulus values between benign and malignant uterine cavity lesions,draw the receiver operating characteristic curve(ROC)of each elastic modulus value for diagnosing benign and malignant uterine cavity lesions,and analyze the application value of vaginal ultrasound combined with elastic imaging in the differential diagnosis of benign and malignant uterine cavity lesions.Results The Emea,Emax,Emin,and Esd of elastic imaging in the malignant lesion group were higher than those in the benign lesion group,with statistical significance(t=28.573,23.996,2.618,17.412,P<0.01);The coincidence rate between malignant lesions detected by transvaginal ultrasound and histopathological diagnosis was 54.3%,elastic imaging examination was 71.4%,and combined examination was 88.6%;The coincidence rate between benign lesions detected by transvaginal ultrasound and histopathological diagnosis was 82.1%,78.6% by elastography,and 92.9% by combined examination.The AUC of benign and malignant lesions diagnosed by transvaginal ultrasound was 0.538,the AUC of elastography was 0.661,and the AUC of combined examination was 0.788.The AUC of combined examination was higher than that of transvaginal ultrasound and elastography(P=0.04).Conclusions Transvaginal ultrasound combined with ultrasound elastography technology can improve the diagnostic accuracy of uterine cavity malignant lesions.
作者
陈宝霞
冯金凤
闫丽丽
毕胜利
武艳娇
Chen Baoxia;Feng Jinfeng;Yan Lili;Bi Shengli;Wu Yanjiao(The Second Hospital Affiliated to Hebei North University,Hebei Province,Zhangjiakou 075100,China;不详)
出处
《疑难病杂志》
CAS
2023年第11期1191-1196,共6页
Chinese Journal of Difficult and Complicated Cases
基金
河北省医学科学研究重点课题(20190865)。
关键词
宫腔病变
经阴道超声
超声弹性成像
联合诊断
Uterine lesion
Transvaginal ultrasound
Ultrasound elasticity imaging
Combined diagnosis