摘要
哮喘是目前世界上较为常见的一种慢性气道疾病,好发于儿童。当前全球气候变化莫测,大量的流行病学研究和实验研究均表明,气象因素的变化可能会引起儿童哮喘的发作和/或加重。气象因素可以通过多种途径作用于哮喘患儿,主要是通过影响大气污染物或过敏原来进一步对哮喘发挥作用,作用机制主要有气道炎症、气道高反应性、氧化应激、肺功能下降等。本文就气象因素与儿童哮喘之间的关系作一综述。
Asthma is a relatively common chronic airway disease in the world,and is most prevalent in children.The current global climate change is unpredictable,and a large number of epidemiological studies and experimental studies have shown that the change of climate factors may cause the attack and/or aggravation of asthma in children.Climate factors can act on children with asthma through a variety of ways,mainly by affecting air pollutants or allergies to further play a role in asthma.The mechanism of action mainly includes airway inflammation,airway hyperresponsiveness,oxidative stress,lung function decline,etc.This review summarizes the relationship between meteorological factors and asthma in childhood.
作者
李玉敏
张玉玲
梁晓平
LI Yumin;ZHANG Yuling;LIANG Xiaoping(Inner Mongolia Medical University,Hohhot,Inner Mongolia Autonomous Region 010000,China;Inner Mongolia Maternity and Child Health Care Hospital,Critical care Department of Inner Mongolia Autonomous Region Children's Hospital,Inner Mongolia Autonomous Region 010000,China)
出处
《中国儿童保健杂志》
CAS
CSCD
2023年第8期873-878,共6页
Chinese Journal of Child Health Care
基金
内蒙古自治区自然科学基金项目(2019MS08109)。
关键词
哮喘
气象因素
儿童
asthma
meteorological factors
children
