摘要
肿瘤治疗不可避免地会产生中枢和周围神经系统的并发症,且相关并发症在时间及剂量上存在聚积效应。因此,早期识别并实施干预对最大程度地减少肿瘤治疗对神经系统的损伤尤为重要。本文系统性地综述了当今肿瘤类疾病主流的治疗方法(包括化学治疗、放射治疗以及免疫治疗)可能发生的神经系统并发症及其MRI特征,有助于指导临床对肿瘤治疗相关神经并发症的早期诊断及肿瘤个体化治疗方案的决策,从而提高肿瘤长期生存患者的生活质量。
Treatment of tumors inevitably produces both central and peripheral nervous system complications,and the associated complications have a cumulative effect in time and dose.Therefore,early identification and intervention are particularly important to minimize the neurological damage of tumor treatment.This article systematically reviews the possible neurological complications of chemotherapy,radiotherapy and immunotherapy,the main treatments for tumor,and their MRI characteristics,which can help guide the early diagnosis of the neurotoxicity and explore the individualized tumor treatment plans,so as to improve the quality of life of the long-term tumor survivors.
作者
何嘉琦
廖伟华
HE Jiaqi;LIAO Weihua(Department of Radiology,Xiangya Hospital,Central South University,Changsha 410008,China;National Clinical Research Center forGeriatric Disorders,Xiangya Hospital,Central South University,Changsha 410008,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2023年第11期170-176,共7页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:82071894)。
关键词
化学治疗
放射治疗
免疫治疗
神经毒性
磁共振成像
chemotherapy
radiotherapy
immunotherapy
neurotoxicity
magnetic resonance imaging
