摘要
牦牛(Bos grunniens)主要分布在海拔3000 m以上的高寒低氧地区,具有“高原之舟”的美称。经过长期的适应性进化,牦牛在生理结构及遗传分子方面表现出高原适应性特征,随着组学技术的广泛应用,进一步揭示了牦牛高原适应机制。文章对牦牛遗传背景、形态、生理高原适应性进化的改变、相应分子遗传和调控机制进行综述,以期为牦牛及其他高原动物低氧适应的研究和高原缺氧疾病的预防和治疗提供新思路。
The yak(Bos grunniens)is mainly distributed in the high cold and low oxygen areas above 3000 m,and has the reputation of"the boat of the plateau".After a long period of adaptive evolution,yaks show the characteristics of plateau adaptability in terms of physiological structure and genetic molecules.With the wide application of omics technology,the plateau adaptation mechanism of yaks has been further revealed.In this paper,the genetic background,morphological changes,molecular genetics and regulatory mechanisms of yak were reviewed,in order to provide new ideas for the study of hypoxic adaptation of yaks and other plateau animals and the prevention and treatment of altitude hypoxic diseases.
作者
倪彬
朱莉
高乐程
尼玛仓决
普布曲珍
苟潇
孔小艳
巴桑珠扎
NI Bin;ZHU Li;GAO Lecheng;Nimacangjue;Pubuquzhen;GOU Xiao;KONG Xiaoyan;Basangzhuzha(School of Life Science and Engineering,Foshan University of Science and Technology,Foshan,528231,China;Faculty of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201,China;Institute of Animal Husbandry and Veterinary Medicine and Tibet Academy of Academy of Agriculture and Animal Husbandry Sciences,Lhasa 850000,China;People’s Government of Shaogang Township,Kangma County,Shigatse,Kangma 857500,China)
出处
《黑龙江畜牧兽医》
北大核心
2023年第23期13-20,130,共9页
Heilongjiang Animal Science And veterinary Medicine
基金
国家自然科学基金项目“连续海拔牛种基因组低氧选择信号与基因调控网络”(32260823)。
关键词
牦牛
低氧
高原适应性
基因
分子机制
yaks
hypoxia
high altitude adaptability
gene
molecular mechanisms
