摘要
目的 探究补气祛瘀解毒汤治疗原发性肝癌对血管内皮生长因子及CD4^(+)/CD8^(+)的影响。方法 选取广州中医药大学金沙洲医院收治的原发性肝癌患者76例,将其按照随机分组法分为对照组与观察组各38例。两组均进行肝动脉化疗栓塞术治疗,对照组术后行常规治疗,观察组加以补气祛瘀解毒汤治疗,对两组的肿瘤标志物水平、免疫功能指标、中医证候积分、不良反应发生率进行对比分析。结果 治疗后,观察组肿瘤标志物水平明显低于对照组(P<0.05);免疫功能指标明显高于对照组(P<0.05);中医证候积分明显低于对照组(P<0.05);不良反应发生率明显低于对照组(P<0.05)。结论 在原发性肝癌患者治疗过程中,采用补气祛瘀解毒汤治疗能取得较佳的效果,可有效使患者肿瘤标志物水平得到降低,使其免疫功能得到调节改善,使其相关症状得到缓解改善,减少不良反应的出现,提高生活质量。
Objective To explore the effect of Buqi Quyu Jiedu Decoction(补气祛瘀解毒汤) on VEGF and CD4^(+)/CD8^(+) in the treatment of primary liver cancer.Methods 76 patients with primary liver cancer in Jinshazhou Hospital were randomLy divided into control group and observation group,38 patients in each group.Both groups were treated with hepatic artery chemoembolization.The control group received routine treatment after operation.The observation group was treated with Buqi Quyu Jiedu Decoction.The levels of tumor markers,immune function indicators,traditional Chinese medicine syndrome scores,the incidence of adverse reactions were compared and analyzed.Results The levels of tumor markers(including VEGF,AFP,CEA) in the observation group were significantly lower than those in the control group(P<0.05),the immune function indexes were significantly higher than those in the control group(P<0.05),the traditional Chinese medicine syndrome score was significantly lower than that of the control group(P<0.05),the incidence of adverse reactions was significantly lower than that of the control group(P<0.05).Conclusion In the treatment of patients with primary liver cancer,the use of Buqi Quyu Jiedu decoction can achieve better results,can effectively reduce the level of tumor markers in patients,improve their immune function,alleviate and improve their symptoms,reduce the occurrence of adverse reactions,and improve their quality of life.It has high use value and is worth popularizing.
作者
符碧荷
李永强
FU Bihe;LI Yongqiang(Jinshazhou Hospital,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510168,Guangdong,China;Cancer Center of Sun Yat sen University,Guangzhou 510030,Guangdong,China)
出处
《实用中医内科杂志》
2023年第11期123-125,共3页
Journal of Practical Traditional Chinese Internal Medicine
基金
广东省医学科研基金项目(201901432)。
