摘要
目的:利用Halcyon直线加速器的锥形束CT(CBCT)对鼻咽癌放射治疗过程中的摆位误差及靶区外放边界进行分析,为Halcyon的鼻咽癌调强放射治疗计划提供临床靶区(CTV)外扩计划靶区(PTV)边界大小参考,提高放射治疗精度和疗效。方法:选取广州中医药大学金沙洲医院2020年5月至2022年6月117例使用Halcyon直线加速器进行容积调强弧形放疗的鼻咽癌患者,采集患者的3861次CBCT图像,然后与CT定位图像进行图像配准,获得床左右方向(Lat)、进出方向(Lng)、升降方向(Vrt)的修正值,进行摆位误差分析。利用靶区外扩公式=2.5∑+0.7δ计算得到PTV的外扩值。结果:Halcyon治疗鼻咽癌的摆位误差分别为:Lat 0.10(0.00,0.10)cm、Lng 0.10(0.00,0.20)cm、Vrt 0.20(0.10,0.30)cm,Lat、Lng和Vrt的CTV外扩PTV的值分别为0.12、0.12、0.09 cm。结论:鼻咽癌患者在Halcyon直线加速器做图像引导治疗时,摆位误差低。
Objective To analyze the target volume margins and positioning errors in the radiotherapy for nasopharyngeal carcinoma(NPC)using the cone-beam computed tomography(CBCT)of Halcyon linear accelerator for providing a reference for the margin from clinical target volume to planning target volume(CTV-to-PTV margin)in the radiotherapy for NPC using Halcyon linear accelerator,hence improving treatment precision and effectiveness.Methods A total of 117 NPC patients who received volumetric modulated arc therapy using Halcyon linear accelerator from May 2020 to June 2022 in Jinshazhou Hospital of Guangzhou University of Chinese Medicine were enrolled.The 3861 CBCT images collected from the patients were matched with the CT images to obtain the correction values of the treatment couch in lateral(Lat),longitudinal(Lng)and vertical(Vrt)directions for positioning error analysis.The CTV-to-PTV margin was obtained by the equation(margin=2.5∑+0.7δ).Results The positioning errors in the radiotherapy for NPC using Halcyon linear accelerator were 0.10(0.00,0.10)cm,0.10(0.00,0.20)cm and 0.20(0.10,0.30)cm in Lat,Lng and Vrt directions,respectively.The CTV-to-PTV margins in Lat,Lng and Vrt directions were 0.12,0.12 and 0.09 cm,respectively.Conclusion Low positioning errors can be achieved for NPC patients undergoing image-guided treatment using Halcyon linear accelerator.
作者
苏洁洪
魏夏平
周子涵
董彦鑫
朱毅
姚宇蔚
刘叶明
黄明超
董晶
黄小伟
SU Jiehong;WEI Xiaping;ZHOU Zihan;DONG Yanxin;ZHU Yi;YAO Yuwei;LIU Yeming;HUANG Mingchao;DONG Jing;HUANGXiaowei(Department of Radiation Oncology,Jinshazhou Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510080,China;Department of Science and Technology,Dongguan University of Technology,Dongguan 523808,China)
出处
《中国医学物理学杂志》
CSCD
2023年第12期1459-1462,共4页
Chinese Journal of Medical Physics
基金
国家自然科学基金青年基金(12004410)。
关键词
鼻咽癌
Halcyon
锥形束CT
摆位误差
靶区外放边界
nasopharyngeal carcinoma
Halcyon
cone-beam computed tomography
positioning error
target volume margin
