摘要
目的分析头颅大动脉及穿支动脉狭窄程度的影响因素。方法选取2022-09—2023-02粤北人民医院收治的100例头颅大动脉及穿支动脉狭窄患者为研究对象,其中大动脉及穿支动脉重度狭窄(狭窄70%及以上)的50例患者为重度组,大动脉及穿支动脉轻中度狭窄(狭窄<70%)的50例患者为轻中度组。收集2组患者的一般临床资料和实验室检查资料,分析头颅大动脉及穿支动脉狭窄程度的影响因素。结果单因素分析显示,重度组患者的年龄、体重指数(BMI)、吸烟率及TC、SVEP1、FPG、UA、Cys C水平均高于轻中度组(P<0.05)。多因素Logistic回归分析显示,BMI、吸烟和SVEP1、FPG、Cys C水平是头颅大动脉及穿支动脉狭窄的独立危险因素(P<0.05)。结论影响头颅大动脉及穿支动脉狭窄程度的独立危险因素主要包括体重指数过高、吸烟和SVEP1、FPG、Cys C水平升高,应早期开展上述指标的监测,以减少急性缺血性脑卒中的发生。
Objective To analyze the factors affecting the degree of great intracranial artery and perforator artery stenosis.Methods From September 2022 to February 2023,100 patients with large great intracranial artery and perforator artery stenosis admitted to Yuebei People’s Hospital were selected as objects,50 patients with severe great intracranial artery and perforator artery stenosis(stenosis 70%or more)were in the severe group,and 50 patients with mild to moderate great intracranial artery and perforator artery stenosis(stenosis less than 70%)were in the mild to moderate group.General clinical data and laboratory test data were collected from the two groups to analyze the factors affecting the degree of stenosis of large skull arteries and perforator arteries.Results Univariate analysis showed that the age,body mass index,smoking rate of the severe patients,TC,SVEP1,FPG,UA,and CysC levels were higher than those in the mild-to-moderate group(P<0.05).Multivariate Logistic regression analysis showed that body mass index,smoking and SVEP1,FPG,and CysC levels were independent risk factors for the degree of stenosis of the great and perforator arteries(P<0.05).Conclusion The independent risk factors affecting the stenosis degree of great and perforator arteries mainly include excessive body mass index,smoking and increased SVEP1,FPG and CysC levels.Early monitoring and intervention of the above indicators should be carried out to reduce the occurrence of acute ischemic stroke.
作者
林盛
LIN Sheng(Yuebei People’s Hospital Affiliated to Shantou University School of Medicine/Yuebei People’s Hospital,Shaoguan 512009,China)
出处
《中国实用神经疾病杂志》
2024年第1期80-84,共5页
Chinese Journal of Practical Nervous Diseases
基金
韶关市卫生健康科研项目(编号:Y23031)。
关键词
头颅大动脉
穿支动脉
狭窄程度
影响因素
急性缺血性脑卒中
Great intracranial artery
Perforator artery
Degree of stenosis
Factors affecting
Acute ischemic stroke
