摘要
目的 :探讨血液灌流(hemoperfusion, HP)联合连续性静脉-静脉血液滤过(continuous venous-venous hemofiltration, CVVH)治疗对感染性休克患者血清乳酸、炎性因子水平及预后的影响。方法 :将100例感染性休克患者随机分为观察组(n=50)和对照组(n=50)。对照组采用CVVH治疗,观察组采用CVVH联合HP治疗。比较2组血清乳酸水平、炎性因子水平及预后情况。结果 :治疗后,观察组血清乳酸水平、炎性因子水平和病死率均低于对照组(均P <0.05)。结论:感染性休克患者采用CVVH联合HP治疗效果较好,利于降低血清乳酸水平,减轻机体炎性反应,改善患者预后。
Objective:To investigate the effects of hemoperfusion(HP)combined with continuous venous-venous hemofiltration(CVVH)therapy on the serum levels of lactate and inflammatory factor and prognosis in patients with infectious shock.Methods:One hundred patients with infectious shock were randomly divided into an observation group(n=50)and a control group(n=50).The control group was treated with CVVH and the observation group was treated with CVVH combined with HP.The serum levels of lactate and inflammatory factorl and prognosis were compared between the two groups.Results:After treatment,the serum levels of lactate and inflammatory factor and the morbidity and mortality rates were lower in the observation group than the control group(all P<0.05).Conclusion:The combination therapy for the patients with infectious shock has better efficacy,can reduce the serum lactate level and the inflammatory reaction of the body and improve the prognosis of patients.
作者
欧阳丽芬
罗丹
王龙海
何青云
康骏
OUYANG Lifen;LUO Dan;WANG Longhai;HE Qingyun;KANG Jun(Department of Critical Care Medicine,Jiangxi TCM-Integrated Hospital,Nanchang 330002,China)
出处
《上海医药》
CAS
2023年第23期61-64,共4页
Shanghai Medical & Pharmaceutical Journal
关键词
感染性休克
血液灌流
血液滤过
血清乳酸
炎性因子
预后
infectious shock
hemoperfusion
hemofiltration
serum lactate
inflammatory factors
prognosis
