摘要
牛磺熊去氧胆酸(TUDCA)是由熊去氧胆酸和牛磺酸结合的产物,主要存在于熊胆中,已被证明具有抗氧化、抗炎和免疫调节等生物活性。在过去的几十年里,TUDCA已成为一种备受关注的天然化合物,因其潜在的生物活性和药理学作用被用于许多领域的研究。为更全面了解TUDCA的抗氧化活性,本文分别从TUDCA抗氧化活性及其调节途径方面进行综述,为TUDCA作为饲料添加剂应用于畜牧生产中提供参考。
Tauroursodeoxycholic acid(TUDCA)is a product of the combination of ursodeoxycholic acid and taurine.It is mainly found in bear bile and has been shown to have biological activities such as anti-oxidation,anti-inflammatory and immune regulation.In the past few decades,TUDCA has become a highly concerned natural compound,which has been used in many fields for its potential biological activity and pharmacological effects.In order to understand the antioxidant activity of TUDCA more comprehensively,this paper reviews the antioxidant activity of TUDCA and its regulation pathway,to provide reference for the application of TUDCA as feed additive in animal husbandry production.
作者
姜敏
王哲奇
金晓
徐元庆
JIANG Min;WANG Zheqi;JIN Xiao;XU Yuanqing(College of Animal Science,Inner Mongolia Agricultural University,Hohhot 010018,China;Institute of Grassland Research,Chinese Academy of Agricultural Sciences,Hohhot 010010,China)
出处
《动物营养学报》
CAS
CSCD
北大核心
2023年第12期7633-7640,共8页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
内蒙古自治区直属高校基本科研业务费项目(BR220135)
内蒙古自治区自然科学基金(2022QN03005)
内蒙古农业大学动物科学学院高水平成果培育专项项目(QT202214)
中国农业科学院草原研究所基本科研业务费专项(1610332022008)。
关键词
牛磺熊去氧胆酸
氧化应激
信号通路
tauroursodeoxycholic acid
oxidative stress
signal pathway
