摘要
目的回顾性分析近10年重庆开州地区儿童下消化道出血的流行病学变化趋势,并对其疾病负担变化进行调查,以期为儿童下消化道出血的精准防控提供理论依据。方法收集2012—2021年重庆开州区人民医院就诊并诊断为儿童下消化道出血患者671例作为研究对象。分析10年间儿童下消化道出血镜检率及常见病因构成以及不同年龄段、不同地区、不同基础病情况的流行病学特征;计算并对比10年内儿童下消化道出血的伤残损失寿命年(YLD)率、早死亡寿命损失年(YLL)率和伤残调整寿命年(DALY)率,并计算年度变化百分比(AAPC)分析疾病负担变化趋势。结果该地区10年间下消化道出血儿童镜检率呈升高趋势(P<0.001);其中较为常见的病因分别为克罗恩病、溃疡性结肠炎和慢性结肠炎。下消化道出血患儿中男童、>18岁以及高血压、肠胃炎占比较高。10年间下消化道出血引起DALY率、YLL率、YLD率均表现为上升趋势(P<0.05)。结论儿童下消化道出血镜检率逐渐升高,男童、高血压以及肠胃炎等基础性疾病是下消化道患病率升高的危险因素;此外,儿童下消化道出血造成的疾病负担也在逐年增加,应引起重视。
Objective To retrospectively analyze the epidemiological trend of children with lower gastrointestinal bleeding in recent 10 years,and investigate the change of their disease burden,so as to provide a theoretical basis for the accurate prevention and control of children′s lower gastrointestinal bleeding.Methods A total of 671 children with"lower gastrointestinal bleeding"who were diagnosed in our hospital from 2012 to 2021 were collected as research subjects.To analyze the microscopic examination rate and common etiology of lower gastrointestinal bleeding in children in the past 10 years,as well as the epidemiological characteristics of different age groups,different regions and different basic diseases;Calculate and compare the rate of disability life lost(YLD),early death life lost(YLL)and disability adjusted life year(DALY)of children with lower gastrointestinal bleeding within 10 years,and calculate the annual change percentage(AAPC)to analyze the change trend of disease burden.Results The microscopic examination rate of children with lower gastrointestinal bleeding showed a trend of increasing in the past 10 years(P<0.001).Among them,the most common causes are Crohn′s disease,ulcerative colitis and chronic colitis.The proportion of children with lower gastrointestinal bleeding was higher in boys,>18 years old,hypertension and gastroenteritis.The DALY rate,YLL rate and YLD rate caused by lower gastrointestinal bleeding in the past 10 years showed an upward trend(P<0.05).Conclusion The microscopic examination rate of lower gastrointestinal bleeding in children was graduallyincreasing,and the prevalence rate of basic diseases such as boys,hypertension and gastroenteritis was increasing;in addition,the disease burden caused by children′s lower gastrointestinal bleeding was also increasing year by year and should be protected.
作者
唐国英
刘青
朱明跃
赵永萍
蒋萍影
杨霖昀
TANG Guoying;LIU Qing;ZHU Mingyue;ZHAO Yongping;JIANG Pingying;YANG Linyun(Chongqing Kaizhou District People′s Hospital(Chongqing Institute of Clinical Prevention and Control of Natural Epidemic Source Diseases in the Three Gorges Reservoir Area),Pediatrics,Chongqing 405400,China)
出处
《公共卫生与预防医学》
2024年第1期100-103,共4页
Journal of Public Health and Preventive Medicine
关键词
儿童
下消化道出血
变化趋势
疾病负担
Children
Lower gastrointestinal hemorrhage
Change trend
Disease burden
