摘要
目的探讨阿托伐他汀钙联合苯磺酸氨氯地平治疗动脉粥样硬化的临床效果。方法选取2020年2月至2023年2月我院收治的74例动脉粥样硬化患者,随机分为对照组(37例,苯磺酸氨氯地平)和观察组(37例,阿托伐他汀钙联合苯磺酸氨氯地平)。比较两组的治疗效果、血脂水平及脂蛋白相关磷脂酶A2(LP-PLA2)水平。结果观察组治疗总有效率、HDL-C水平明显高于对照组,TC、TG、LDL-C及LP-PLA2水平明显低于对照组(P<0.05)。结论阿托伐他汀钙联合苯磺酸氨氯地平治疗动脉粥样硬化的效果显著,对调节患者血脂代谢、改善血管炎性状态具有积极作用。
Objective To explore the clinical effect of atorvastatin calcium combined with amlodipine besylate in the treatment of atherosclerosis.Methods 74 patients with atherosclerosis admitted to our hospital from February 2020 to February 2023 were selected and randomly divided into control group(37 cases,amlodipine besylate)and observation group(37 cases,atorvastatin calcium combined with amlodipine besylate).The treatment effect,blood lipid level and lipoprotein-associated phospholipase A2(LP-PLA2)level were compared between the two groups.Results The total effective rate of treatment and HDL-C level in the observation group were significantly higher than those in the control group,and the TC,TG,LDL-C and LP-PLA2 levels were significantly lower than those in the control group(P<0.05).Conclusions Atorvastatin calcium combined with amlodipine besylate in the treatment of atherosclerosis has significant effect,and also has positive effect on the regulation of lipid metabolism and improvement of vascular inflammatory state in patients.
作者
陈君
尹俊锋
逄涛
CHEN Jun;YIN Junfeng;PANG Tao(Department of Neurology,Zhengzhou First People's Hospital,Zhengzhou 450004,China)
出处
《临床医学工程》
2024年第1期37-38,共2页
Clinical Medicine & Engineering
基金
河南省医学科技攻关计划联合共建项目(2018020729)。
