摘要
目的了解中医药治疗下肢动脉硬化闭塞症研究现状及发展趋势,为相关研究提供参考。方法检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)收录的1992年9月18日-2022年9月18日中医药治疗下肢动脉硬化闭塞症研究文献。采用NoteExpress3.6.0软件管理、去重,采用Excel2019分析发文量趋势,采用VOSviewer1.6.18.0和CiteSpace6.1.R6软件对纳入文献作者、机构及关键词进行共现、聚类、时间线及突现分析并绘制知识图谱。结果共纳入文献1095篇,发文量总体呈上升趋势;涉及1915位作者,发文最多的为陈柏楠,形成了以奚九一、曹烨民、葛建立等为核心的研究团队;主要研究机构有山东中医药大学、北京中医药大学、黑龙江中医药大学等,但各机构间合作较少;高频关键词有动脉硬化、糖尿病、临床疗效、脱疽、血液流变学等,形成气虚血瘀、四妙勇安汤、血管新生等13个聚类,研究热点为中医外治法、临床疗效、血脉瘀阻证、用药规律、补阳还五汤。结论1992-2022年中医药治疗下肢动脉硬化闭塞症研究热度逐渐升高;基于大数据平台的基因检测、分子生物学等现代研究为该领域研究热点;中医内、外治法联合的中医特色综合治疗,以及结合介入治疗等技术的中西医结合多学科交叉研究为发展趋势。
Objective To understand the research status and development trend of TCM in the treatment of lower limb arteriosclerosis obliterans(LLASO);To provide reference for related research.Methods The literature on the treatment of LLASO by TCM was retrieved from CNKI,Wanfang Data and VIP from September 18,1992 to September 18,2022.NoteExpress 3.6.0 was used to manage and remove repetition.Excel 2019 was used to analyze the trend of the number of articles published.VOSviewer 1.6.18.0 and CiteSpace 6.1.R6 were used to analyze the co-occurrence,clustering,timeline and emergence of the included authors,institutions and keywords,and knowledge graph was drawn.Results A total of 1095 articles were included,and the number of articles published showed an overall upward trend;1915 authors were involved,and the author with the most articles was Chen Bainan,forming research teams with Xi Jiuyi,Cao Yemin and Ge Jianli as the cores respectively;the main research institutions were Shandong University of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Heilongjiang University of Chinese Medicine and so on,but there was little cooperation among them.High-frequency keywords included arteriosclerosis,diabetes,clinical efficacy,gangrene,hemorheology,etc.,forming 13 clusters such as qi deficiency and blood stasis,Simiao Yong'an Decoction,angiogenesis and so on.The focus of research was external treatment of TCM,clinical efficacy,blood stasis syndrome,medication law,Buyang Huanwu Decoction.Conclusion The research heat of TCM in the treatment of LLASO has gradually increased,and the modern research in this field from 1992 to 2022,such as gene detection and molecular biology based on big data platform,is the research hotspot in this field.The development trend is the combination of internal treatment and external treatment of TCM,as well as the interdisciplinary research of integrated traditional Chinese and Western medicine combined with interventional therapy and other techniques.
作者
邓俊林
曹芳
王御震
蔡惠群
曹烨民
DENG Junlin;CAO Fang;WANG Yuzhen;CAI Huiqun;CAO Yemin(Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Traditional Chinese Medicine-Integrated Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200082,China;Shanghai Municipal Hospital of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200071,China)
出处
《中国中医药信息杂志》
CAS
CSCD
2024年第2期70-77,共8页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家科技重大专项(2019ZX09201004-002-091)
国家自然科学基金(82174382)
上海市2020年度科技创新行动计划项目(20Z21900200)
全国基层名老中医药专家曹烨民传承工作室建设项目(Z155080000004)。
