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光化学疗法联合干扰素治疗蕈样肉芽肿30例 被引量:3

Photochemotherapy combined with interferon in the treatment of mycosis fungoides:a report of 30cases
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摘要 对30例蕈样肉芽肿(MF)患者(大多数属早期病程),用光化学疗法(PUVA)及小剂量α-干扰素进行联合治疗,PUVA的平均治疗剂量为102.8J/cm2,α-干扰素的平均治疗量为6×106U/周。治疗后总有效率为93.3%,其中完全缓解率为36.7%,无严重不良反应。结果证明PUVA联合干扰素治疗MF是安全有效的。 Mycosis fungoides(MF)is an epidermotropic form of non-Hodgkin's cutaneous T-cell lymphoma.We treated30patients with MF using PUVA combined with low dosage of IFN-α.The mean dosage of PUVA was102.8J /cm 2 .The aver-age dose of recombinant IFN-αwas6×10 6 U weekly.The overall response rate was93.3%,with36.7%of complete remis-sion.No severe adverse effect was encountered.It is suggested that PUVA is an effective and comparatively safe therapy.
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2002年第12期767-769,共3页 Journal of Clinical Dermatology
关键词 光化学疗法 干扰素 治疗 蕈样肉芽肿 PUVA interferon mycosis fungoides
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