摘要
甲状腺相关性眼病(Thyroid associated ophthalmopathy,TAO)是最常见的眼眶疾病。作为一种自身免疫性疾病,TAO的基本病理过程是眼眶组织免疫细胞的浸润、眼眶成纤维细胞的激活以及眼眶纤维细胞和淋巴细胞的增殖和分化。淋巴细胞是引起甲状腺眼病发病的关键,但其机制尚不完全清楚。核磁共振成像(Magnetic resonance imaging,MRI)对软组织分辨率高,已经广泛应用于TAO,从多种角度为TAO的分期及分级等提供更客观的信息。因此,本文通过总结淋巴细胞在TAO的作用和MRI技术在TAO应用,以指导临床决策,并为将来的研究提供参考方向。
Thyroid associated ophthalmopathy(TAO)is the most common orbital disease.As an autoimmune disease,the basic pathological process of TAO is the infiltration of orbital immune cells,activation of orbital fibroblasts,proliferation and differentiation of orbital fibroblasts and lymphocytes.Lymphocyte is the key to the pathogenesis of thyroid eye disease,but its mechanism is not fully understood.Magnetic resonance imaging(MRI)has been widely used in TAO due to its high soft tissue resolution,providing more objective information for the staging and grading of TAO from various perspectives.Therefore,this paper summarizes the role of lymphocytes in TAO and the application of MRI technology in TAO to guide clinical decision-making and provide reference direction for future research.
作者
张明巧
龙健
Zhang Ming-qiao;Long Jian(Department of Endocrinology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)
出处
《四川生理科学杂志》
2024年第2期469-472,共4页
Sichuan Journal of Physiological Sciences
关键词
甲状腺相关性眼病
磁共振成像
淋巴细胞
thyroid-associated ophthalmopathy
Magnetic resonance imaging
lymphocyte
