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重症肺炎伴感染性休克行早期限制性液体复苏的治疗研究 被引量:1

Treatment Study of Early Restricted Fluid Resuscitation for Severe Pneumonia with in fectious Shock
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摘要 目的探索早期限制性液体复苏治疗重症肺炎伴感染性休克临床疗效。方法收集本院2021年1月—2022年12月收治的重症肺炎伴感染性休克患者60例作为本次研究对象,并按随机信封抽签法分为对照组和观察组,每组30例。其中,对照组采用常规液体复苏治疗,观察组采用早期限制性液体复苏治疗。观察两组患者各项指标变化。结果观察组总补液、输入胶体量、早期复苏时间提示数值更低,表示差异有统计学意义(P<0.05)。治疗前两组患者血红蛋白、红细胞比容、凝血酶原时间指标,差异无统计学意义(P>0.05);治疗后观察组患者指标优于对照组,表示差异有统计学意义(P<0.05)。治疗前两组患者PaO_(2)/FiO_(2)、CRP指标,差异无统计学意义(P>0.05);治疗后观察组患者PaO_(2)/FiO_(2)、CRP指标优于对照组,表示差异有统计学意义(P<0.05)。结论早期限制性液体复苏对于重症肺炎伴感染性休克治疗效果显著,可以改善患者生理体征,优化凝血酶原时间,促使患者尽快恢复生理机能指标,具有较高应用价值。 Objective To explore clinical effect of early restrictive fluid resuscitation in treatment of severe pneumonia with septic shock.Methods The paper chose 60 patients with severe pneumonia and septic shock in our hospital from January 2021 to December 2022 as study subjects for data analysis,and divided them into two groups randomly by envelope drawing.Control group was treated with routine fluid resuscitation treatment and observation group with early restrictive fluid resuscitation treatment.Changes in various indicators of patients were observed.Results Observation group showed lower values for total fluid replacement,colloid input and early recovery time,indicating difference(P<0.05).There was no difference in hemoglobin,hematocrit,and prothrombin time indicators of patients before treatment(P>0.05).Observation group(after treatment)had better indicators,indicating difference(P<0.05).There was no difference in values of PaO_(2)/FiO_(2)and CRP indicators(before treatment)(P>0.05).Observation group showed better indicator improvement(after treatment),indicating difference(P<0.05).Conclusion Early restrictive fluid resuscitation can achieve significant curative effect for severe pneumonia with septic shock,can improve physiological signs,optimize prothrombin time,and promote recovery of physiological indicators of patients as soon as possible,which has high application value.
作者 刘滨 黄彩英 叶先钦 LIU Bin;HUANG Caiying;YE Xianqin(Guangdong Provincial Agricultural Reclamation Center Hospital,Zhanjiang,Guangdong 524000)
出处 《智慧健康》 2023年第31期29-32,共4页 Smart Healthcare
关键词 重症肺炎 感染性休克 早期限制性液体复苏 Severe pneumonia in fectious shock Early restrictive fluid resuscitation
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