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多发性骨髓瘤化疗患者自我调节疲乏对化疗耐受能力的影响

Effect of self-regulatory fatigue on chemotherapy tolerance in patients with multiple myeloma
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摘要 目的了解多发性骨髓瘤(MM)化疗患者自我调节疲乏现状,分析其对患者化疗耐受能力的影响。方法采用便利抽样法,抽取2020年1月至2022年1月四川大学华西医院收治的105例MM患者为研究对象,采用自我调节疲乏量表(SRF-S)、癌症体验和效能量表(CEES)、癌症患者自我管理测评量表评估患者自我疲乏、癌症自我管理情况。观察MM化疗患者化疗耐受能力,分析MM化疗患者自我调疲乏对化疗耐受能力的影响。结果本研究共纳入105例MM患者,共发放问卷105份,有效回收100份,有效回收率为95.24%。100例MM患者SRF-S评分为(53.28±11.14)分;CEES量表的癌症体验评分为(46.63±12.82)分,控制效能评分为(35.47±7.51)分;平均自我管理评分为(157.54±20.93)分。化疗耐受能力差组SRF-S评分高于化疗耐受能力良好组,差异有统计学意义(P<0.05);经点二列相关性检验,SRF-S评分与MM化疗患者化疗耐受能力呈正相关(r>0,P<0.01)。结论自我调节疲乏与MM化疗患者的化疗耐受能力存在明显相关性,护理人员可根据患者自我调节疲乏状况实施有效干预,提高化疗耐受能力。 Objective To investigate the status quo of self-regulatory fatigue in patients with multiple myeloma(MM)chemotherapy,and to analyze its effect on chemotherapy tolerance.Methods A total of 105 MM patients admitted to West China Hospital of Sichuan University from January 2020 to January 2022 were selected by convenient sampling method.Self-regulated fatigue scale(SRF-S),cancer experience and efficacy scale(CEES)and cancer patient self-management assessment scale were used to evaluate patients’self-fatigue and cancer self-management.The chemotherapy tolerance of MM patients and the effect of self-regulating fatigue on chemotherapy tolerance of MM patients were observed and analyzed.Results A total of 105 MM patients were included in this study.A total of 105 questionnaires were sent out,and 100 were effectively recovered,with an effective recovery rate of 95.24%.The SRF-S score of 100 MM patients was(53.28±11.14)points.The cancer experience score of CEES was(46.63±12.82)points,and the control efficacy score was(35.47±7.51)points.The average self-management score was(157.54±20.93)points.The SRF-S score of poor chemotherapy tolerance group was higher than that of good chemotherapy tolerance group,and the difference was statistically significant(P<0.05).By point two-column correlation test,SRF-S score was positively correlated with chemotherapy tolerance of MM patients(r>0,P<0.01).Conclusion There is a significant correlation between self-regulated fatigue and chemotherapy tolerance in MM patients.Nursing staff can implement effective intervention according to patients’self-regulated fatigue status to improve chemotherapy tolerance.
作者 王薇 邱娟 沈恺 WANG Wei;QIU Juan;SHEN Kai(Department of Hematology,West China School of Nursing,Sichuan UniversityWest China Hospital of Sichuan University,Sichuan Province,Chengdu 610000,China)
出处 《中国医药导报》 CAS 2024年第5期61-65,共5页 China Medical Herald
基金 四川省自然科学基金资助项目(2022NSFSC1463)。
关键词 多发性骨髓瘤 化疗 化疗耐受能力 自我调节疲乏 癌症体验和效能 自我管理 Multiple myeloma Chemotherapy Chemotherapy tolerance Self-regulation fatigue Cancer experience and efficacy Self management
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