摘要
目的 了解深圳地区2018—2022年初治HIV/AIDS患者基线特征,为预防和控制AIDS提供依据。方法 回顾性分析深圳市第三人民医院2018—2022年收治的初治HIV/AIDS患者资料,总结其流行病学特点。结果 2018—2022年收治的初治HIV/AIDS患者共8 881例,患者年龄主要集中在25~49岁,占总病例数的71.83%;5年间年龄>50岁患者比例从8.05%上升至11.89%;患者文化程度以大专/本科及以上为主且所比例逐年上升;患者婚姻状况以未婚者居多且所占比例例逐年上升;感染途径以同性传播为主。治疗前基线CD4+T细胞计数<200个/μL的患者比例从36.68%下降至34.94%;治疗前基线HIV载量<104IU/μL患者比例从6.18%上升至10.88%。新报告病例中确证30 d内抗逆转录病毒治疗(antiretroviral treatment,ART)启动率为63.55%。调查的2 314例患者中性伴/配偶HIV检测率为58.56%。结论 深圳地区2018—2022年新报告HIV/AIDS病例数总体呈下降趋势;应继续关注老年人、青少年2类重点人群的感染情况;未婚、同性传播的患者比例逐年上升;性伴/配偶HIV检测率及ART快速启动率有待进一步提高并存在很大挑战。
Objective To understand the baseline characteristics of newly diagnosed HIV/AIDS patients in Shenzhen from 2018 to 2022,and provide evidence for the prevention and control of AIDS.Methods Retrospective analysis of the clinical data of newly diagnosed HIV/AIDS patients treated at The Third People’s Hospital of Shenzhen,a major healthcare facility for HIV/AIDS patients in Shenzhen,from 2018 to 2022,and summarizing their epidemiological characteristics.Results There were 8881 newly diagnosed HIV/AIDS patients from 2018 to 2022,mainly aged 25 to 49 years(71.83%).The proportion of patients over 50 years old infected with HIV/AIDS increased from 8.05%to 11.89%.The education level was mainly junior college/bachelor’s degree or above,and this proportion has been increasing year by year.The majority of patients were unmarried and this proportion has also been increasing annually.The main route of infection was homosexual transmission.The proportion of HIV-infected patients with CD4+T cell count<200/μL at baseline decreased from 36.68%to 34.94%.The proportion of HIV-infected patients with HIV viral load 22 generally showed a downward trend;attention should continue to be paid to the 2 key groups,the elderly and adolescents;the proportion of unmarried and homosexual patients has been increasing annually;there are still great challenges in further improving the HIV testing rate among sexual partners/spouses and rapid initiation of treatment.200/μL at baseline decreased from 36.68%to 34.94%.The proportion of HIV-infected patients with HIV viral load<104 IU/mL at baseline increased from 6.18%to 10.88%.The ART start rate within 30 days of diagnosis among newly reported HIV/AIDS cases from 2018 to 2022 was 63.55%.The HIV testing rate among sexual partners and spouses of the 2314 HIV-infected individuals surveyed was 58.56%.Conclusions The newly reported HIV/AIDS cases in Shenzhen from 2018 to 2022 generally showed a downward trend;attention should continue to be paid to the 2 key groups,the elderly and adolescents;the proportion of unmarried and homosexual patients has been increasing annually;there are still great challenges in further improving the HIV testing rate among sexual partners/spouses and rapid initiation of treatment.
作者
石义容
陈伟梅
朱玉玲
张丽媛
王福祥
何云
SHI Yirong;CHEN Weimei;ZHU Yuling;ZHANG Liyuan;WANG Fuxiang;HE Yun(Department of Infectious Diseases and Immunology,The Third People’s Hospital of Shenzhen,518112,China)
出处
《传染病信息》
2023年第6期521-526,共6页
Infectious Disease Information
基金
国家自然科学基金(2022J0730)。
关键词
艾滋病毒
艾滋病
流行特征
抗逆转录病毒治疗
初次治疗
human immunodeficiency virus
acquired immunodeficiency syndrome
epidemiological characteristics
antiretroviral therapy
initial treatment
