摘要
目的比较生物陶瓷材料iRoot BP Plus与三氧化矿物聚合物(MTA)用作牙齿活髓切断术盖髓剂的疗效差异。方法检索PubMed、Web of Science、Cochrane Library、CNKI、万方数据库和维普数据库中收录的iRoot BP Plus与MTA用于牙齿活髓切断术治疗的随机对照试验(RCT),检索时间为数据库建库至2023年3月。由2名成员严格按照纳入和排除标准独立进行筛选,结局指标包括临床成功率、盖髓操作时间、牙本质桥形成率及牙变色率。利用Cochrane偏倚风险评价工具进行文献质量评价,使用Stata 15.0软件对被纳入的文献进行Meta分析。结果最终纳入18篇RCT,Meta分析结果显示:1)术后3、6、12个月iRoot BP Plus组与MTA组之间临床成功率的差异无统计学意义(P>0.05);2)iRoot BP Plus组的盖髓操作时间明显小于MTA组(P<0.05);3)术后3个月,iRoot BP Plus组的牙本质桥形成率高于MTA组(P<0.05);4)末次随访iRoot BP Plus组牙变色率显著低于MTA组(P<0.05)。结论iRoot BP Plus用于牙齿活髓切断术的临床成功率与MTA相近,但较MTA盖髓操作时间更短,发生牙变色的概率更低。
Objective This study aims to compare the efficacy of iRoot BP Plus and MTA as pulp capping agents for vital pulp therapy.Methods Randomized controlled trials(RCTs)of iRoot BP Plus and MTA in the treatment of pulpotomy were searched in PubMed,Web of Science,Cochrane Library,CNKI,Wanfang,and VIP databases from the establishment to March 2023.Two members conducted independent screening according to the inclusion and exclusion criteria.The outcome indicators included clinical success rate,pulp capping operation time,dentin bridge formation rate,and tooth discoloration rate.The Cochrane bias risk assessment tool was used to evaluate the quality of the literature,and Stata 15.0 was used for meta-analysis.Results A total of 18 RCTs were included.The results of meta-analysis showed 1)no significant difference in the clinical success rate between iRoot BP Plus group and MTA group at 3,6,and 12 months after the operation(P>0.05).2)The operation time of iRoot BP Plus was significantly shorter than that of MTA(P<0.05).3)The formation rate of dentin calcified bridge in the iRoot BP Plus group was higher than that in the MTA group at 3 months after the operation(P<0.05).4)At the last follow-up,the tooth discoloration rate of the iRoot BP Plus group was significantly lower than that of the MTA group(P<0.05).Conclusion The clinical success rate of iRoot BP Plus for pulpotomy is similar to that of MTA,but it has shorter pulp-capping operation time and lower probability of tooth discoloration than MTA pulp capping.
作者
杨岩朵
陈红
许祖达
赵媛
Yang Yanduo;Chen Hong;Xu Zuda;Zhao Yuan(School of Stomatology,Lanzhou University,Lanzhou 730000,China)
出处
《国际口腔医学杂志》
CAS
CSCD
北大核心
2024年第2期176-186,共11页
International Journal of Stomatology
基金
甘肃省卫生健康行业科研项目(GSWSKY2023-33)
兰州大学医学教育创新发展项目(lzuyxcx-2022-166)。
