摘要
口腔再生医学是近年发展起来的一门新兴学科,它将再生医学的基本理论和方法引入口腔医学领域,研究口腔颌面部各种组织器官的正常组织特征与功能以及创伤修复与再生机制,以改善或恢复病损口腔组织和器官的结构与功能,已成为当前口腔科学领域发展最快的交叉学科。锶为人体的必需微量元素,与多种生理功能有关,可用作骨质疏松症的预防性治疗;锶离子的释放对于预防破骨细胞活化和促进成骨细胞分化具有直接作用,也在组织免疫方面发挥着重要作用,能够促进骨骼的生长发育,已成为口腔再生领域的研究热点。本文结合锶元素对生物材料性能的改变,分析现有问题,对锶元素促成骨机制及其在口腔再生医学中的应用进行综述。
Oral regenerative medicine is a new discipline developed in recent years.It introduces the basic theories and methods of regenerative medicine into the field of stomatology to explore the normal tissue characteristics and functions of various tissues and organs in oral and maxillofacial region and the mechanism of wound repair and regeneration,so as to improve or restore the structure and function of damaged oral tissues and organs.It has become the fastest-growing interdisciplinary subject in the field of stomatology.Strontium is an essential trace element in human body,which is related to many physiological functions and can be used as a preventive treatment for osteoporosis.The release of strontium ions plays a direct role in preventing osteoclast activation and promoting osteoblast differentiation,also plays an important role in tissue immunity,and promotes bone growth and development.Therefore,it has become a research hotspot in the field of oral regeneration.This paper analyzes the existing problems in combination with the changes of strontium on the properties of biomaterials,and summarize the mechanism of strontium promoting bone formation and its application in oral regenerative medicine.
作者
董昕玥
张晓明
刘念
马向瑞
DONG Xinyue;ZHANG Xiaoming;LIU Nian;MA Xiangrui(Department of Prosthodontics,Binzhou Medical University Hospital,Shandong,Binzhou 256600,China)
出处
《中国医药科学》
2024年第3期37-40,共4页
China Medicine And Pharmacy
基金
山东省自然科学基金(ZR2018BH026)。
关键词
锶
骨缺损
骨结合
骨再生
牙周
Strontium
Bone defect
Osseointegration
Bone regeneration
Periodontal
