摘要
目的:建立灯芪通脉颗粒的指纹图谱法,指认共有成分并评价质量。方法:使用Diamonsil C18色谱柱(4.6 mm×250 mm,5μm),流动相为水(含0.1%磷酸)-乙腈,梯度洗脱,检测波长为230nm。对10批灯芪通脉颗粒指纹图谱分析,并建立共有模式计算样品间的相似度。结果:样品具有较高的相似性。结论:本方法可用于评价灯芪通脉颗粒质量。
Objective:To establish a fingerprinting method of Deng-Qi-Tong-Mai Granule for identifying common components and evaluating the quality.Method:The Diamonsil C18 chromatographic column(4.6 mm×250 mm,5μm)was used with a mobile phase consisting of water(containing 0.1%phosphoric acid)and acetonitrile in a gradient elution mode,with a detection wavelength of 230 nm.Fingerprint analysis was conducted on ten batches of Deng-Qi-Tong-Mai Granule,and a common pattern was established to calculate the similarity between the samples.Results:The samples exhibited high similarity.Conclusion:This fingerprinting method can be used to evaluate the quality of Deng-Qi-Tong-Mai Granule.
作者
台晶杰
甄会贤
张凤
王小露
张虹
Tai Jing-jie;Zhen Hui-xian;Zhang Feng;Wang Xiao-lou;Zhang Hong(ShanXi Pharmaceutical Vocational College,Taiyuan 030031,China)
出处
《北方药学》
2024年第1期5-8,共4页
Journal of North Pharmacy
关键词
指纹图谱
高效液相色谱
灯芪通脉颗粒
质量评价
fingerprint
high performance liquid chromatography
Deng-Qi-Tong-Mai Granule
quality evaluation
