The impact of human umbilical cord-derived mesenchymal stem cells on the pancreatic function of type 2 diabetic mice and their regulatory role on NLRP3 inflammasomes

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摘要 Objective To investigate the effect and regulation of umbilical cord-derived mesenchymal stem cells(UCMSCs)on islets function and NOD-like receptor family,pyrin domain containing 3(NLRP3)and autophagy in type 2 diabetic mellitus(T2DM)mice.Methods Experimental study.Twenty,8-week-old male C57BL/6J mice were selected and divided into a normal control group(n=5)and a high-fat feeding modeling group(n=15).

作者王杰 WANG Jie(Dept Endocrinol,1st Med Center,Chin PLA General Hosp,Beijing 100853)

机构地区 Dept Endocrinol

出处《China Medical Abstracts(Internal Medicine)》 2023年第4期209-210,共2页 中国医学文摘（内科学分册（英文版）

关键词 NLRP3 DIABETIC function

分类号 R587.1 [医药卫生—内分泌]

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China Medical Abstracts(Internal Medicine)

2023年第4期

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The impact of human umbilical cord-derived mesenchymal stem cells on the pancreatic function of type 2 diabetic mice and their regulatory role on NLRP3 inflammasomes

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