摘要
目的利用光学相干断层扫描血管成像(OCTA)探究血管性麻痹性斜视患者麻痹期与恢复期黄斑区血管密度(VD)是否发生变化,分析血管性麻痹性斜视是否对黄斑区血流产生影响。方法本研究采用横断面观察实验设计,共纳入血管性麻痹性斜视患者30例,这些患者在2022年12月至2023年10月于内蒙古自治区人民医院眼科就诊。利用OCTA技术对麻痹期和恢复期患者进行黄斑区6 mm×6 mm扫描。对所得图像进行定量分析,计算视网膜浅层毛细血管(SCP)和深层毛细血管(DCP)的血流密度,以及无灌注区面积(FAZ)。结果30例血管性麻痹性斜视患者,平均恢复时间为(60.87±16.77)d。第六神经麻痹最常见。对比麻痹眼与非麻痹眼的OCTA结果发现,麻痹眼的SCP明显低于对侧眼,偏斜角度越大,眼动受限越严重,SCP血流密度越低。麻痹期与恢复期相比较,SCP恢复后明显增加。结论血管性麻痹性斜视患者麻痹眼黄斑区血流密度减低,缺血程度与眼运动受限程度相对应。
Objective To investigate the changes in macular vascular density(VD)in patients with vascular paralytic strabismus during paralysis and recovery periods using optical coherence tomography angiography(OCTA),and to analyze whether paralytic strabismus affects macular blood flow.Method This study adopted a cross-sectional observation experimental design and included 30 patients with vascular paralytic strabismus who visited the ophthalmology department of Inner Mongolia Autonomous Region People's Hospital from December 2022 to October 2023.Using OCTA technology to assess the macular area of these patients during their paralysis and recovery periods×6 scans.Quantitative analysis was performed on the obtained images to calculate the blood flow density of shallow and deep retinal capillaries(SCP),as well as the area without perfusion(FAZ).Results The average recovery time of 30 patients with paralytic strabismus was(60.87±16.77)days.Sixth nerve paralysis is the most common type.Comparing the OCTA results of paralyzed and non paralyzed eyes,it was found that the SCP of paralyzed eyes was significantly lower than that of the contralateral eye.The larger the deviation angle,the more severe the eye movement limitation,and the lower the SCP value.Compared with the recovery period,SCP significantly increased after recovery.Conclusion In patients with paralytic strabismus,the blood flow density in the macular area of the paralyzed eye decreases,and the degree of ischemia corresponds to the degree of eye movement limitation.
作者
李秀慧
杜红艳
LI Xiuhui;DU Hongyan(Inner Mongolia University of Science and Technology Baotou Medical College,Baotou 014040 China;Inner Mongolia Autonomous Region People's Hospital,Hohhot 010017 China)
出处
《内蒙古医学杂志》
2024年第1期5-10,共6页
Inner Mongolia Medical Journal
关键词
血管性麻痹性斜视
光学相干断层扫描血管成像
黄斑区血流变化
vascular paralysis strabismus
optical coherence tomography vascular imaging
macular area vascular density
