摘要
能量代谢是细菌生长繁殖的基础,也是影响其致病的重要因素。文章综述了细菌能量代谢各环节对其的生理意义,讨论了不同细菌能量代谢相关基因或酶缺失后对其致病性影响的意义以及存在的问题。能量代谢的相关基因或酶有望成为抗菌药物的新靶标位点,为细菌性疾病的预防和细菌耐药性提供新思路。
Energy metabolism is the basis for bacterial growth and reproduction,and it is also an important factor affecting its pathogenicity.In this paper,the physiological significance of each link of bacterial energy metabolism is reviewed,and the significance and existing problems of the pathogenicity of different bacterial energy metabolism-related genes or enzymes are discussed.Genes or enzymes related to energy metabolism are likely to become new target sites for antibiotics,providing new ideas for the prevention of bacterial diseases.
作者
赵嘉俊
袁建波
王璐
黄健(综述)
闵迅(审校)
ZHAO Jiajun;YUAN Jianbo;WANG Lu;HUANG Jian;MIN Xun(School of Laboratory Medicine,Zunyi Medical University,Zunyi,Guizhou 563003,China;Department of Clinical Laboratory,Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou 563003,China)
出处
《国际检验医学杂志》
CAS
2024年第7期867-871,共5页
International Journal of Laboratory Medicine
基金
国家自然科学基金项目(32060035)。
关键词
细菌
能量代谢
三磷酸腺苷
致病性
bacteria
energy metabolism
adenosine triphosphate
pathogenicity
